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Urispas and Actonel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Urispas (flavoxate hydrochloride) and Actonel (risedronate sodium). Common drug interactions include arteriovenous fistula occlusion among females.

The phase IV clinical study analyzes what interactions people have when they take Urispas and Actonel. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Urispas?

Urispas has active ingredients of flavoxate hydrochloride. eHealthMe is studying from 598 Urispas users. Check the latest studies of Urispas.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

On Jun, 17, 2026

23 people who take Urispas and Actonel together, and have interactions are studied.

Urispas and Actonel drug interactions.

What are the common drug interactions of Urispas and Actonel, by gender? *:

female:

  1. Arteriovenous fistula occlusion
  2. Cough
  3. Limb injury
  4. Muscle strain (an injury to a muscle in which the muscle fibres tear)
  5. Productive cough
  6. Renal pain (kidney pain)
  7. Chronic myeloid leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood)
  8. Bacterial test positive
  9. Blood creatinine increased
  10. Blood pressure increased

male:

n/a

What are the common drug interactions of Urispas and Actonel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pain in extremity
  2. Peripheral swelling
  3. Rhinorrhoea (watery mucus discharge from the nose)
  4. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  5. Thrombosis (formation of a blood clot inside a blood vessel)
  6. Blue toe syndrome (blue toe syndrome is a lack of blood flow to the toes causing a blue discoloration)
  7. Limb injury
  8. Muscle strain (an injury to a muscle in which the muscle fibres tear)
  9. Productive cough
  10. Renal pain (kidney pain)

50-59:

  1. Chronic myeloid leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood)

60+:

  1. Bacterial test positive
  2. Chronic myeloid leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood)
  3. Lung infection
  4. Night sweats (sweating in night)
  5. Septic shock (shock due to blood infection)

What are the existing conditions these people have? *

  1. High Blood Pressure: 17 people, 73.91%
  2. Pain In Extremity: 11 people, 47.83%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Urispas and Actonel?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Urispas and Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Urispas:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Urispas and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actonel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on flavoxate hydrochloride and risedronate sodium (the active ingredients of Urispas and Actonel, respectively), and Urispas and Actonel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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