Ursodeoxycholic acid and Pegintron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ursodeoxycholic acid (ursodiol) and Pegintron (peginterferon alfa-2b). Common drug interactions include anaemia among females and neutrophil count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Ursodeoxycholic acid and Pegintron. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Ursodeoxycholic acid?

Ursodeoxycholic acid has active ingredients of ursodiol. It is often used in biliary cirrhosis primary. eHealthMe is studying from 7,528 Ursodeoxycholic acid users. Check the latest studies of Ursodeoxycholic acid.

What is Pegintron?

Pegintron has active ingredients of peginterferon alfa-2b. It is often used in hepatitis c. eHealthMe is studying from 10,326 Pegintron users. Check the latest studies of Pegintron.



On Jul, 25, 2026

33 people who take Ursodeoxycholic acid and Pegintron together, and have interactions are studied.

Ursodeoxycholic acid and Pegintron drug interactions.

What are the common drug interactions of Ursodeoxycholic Acid and Pegintron, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Decreased appetite
  3. Nausea (feeling of having an urge to vomit)
  4. Anxiety disorder
  5. Blood creatinine increased
  6. Haemoglobin decreased
  7. Insomnia (sleeplessness)
  8. Platelet count decreased
  9. Drug eruption (adverse drug reaction of the skin)
  10. Palpitations (feelings or sensations that your heart is pounding or racing)

male:

  1. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  2. Platelet count decreased
  3. Insomnia (sleeplessness)
  4. Pyrexia (fever)
  5. Suicidal ideation
  6. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  7. Abdominal discomfort
  8. Abdominal distension
  9. Blood uric acid increased
  10. Cytomegalovirus infection

What are the common drug interactions of Ursodeoxycholic Acid and Pegintron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anxiety disorder
  2. Decreased appetite
  3. Haemoglobin decreased
  4. Insomnia (sleeplessness)
  5. Nausea (feeling of having an urge to vomit)
  6. Blood creatinine increased
  7. Blood uric acid increased
  8. Eczema asteatotic (severe dry skin- during the winter months and in the elderly)
  9. Platelet count decreased
  10. Urinary tract infection

40-49:

  1. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  2. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  3. Platelet count decreased
  4. Schizophrenia (a mental disorder characterized by a breakdown of thought processes)

50-59:

  1. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  2. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  3. Blood creatinine increased
  4. Erythema (redness of the skin)
  5. Gastric ulcer (stomach ulcer)
  6. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  7. Platelet count decreased
  8. Rash
  9. Rectal cancer (cancer of rectum)
  10. Renal disorder (kidney disease)

60+:

  1. Anaemia (lack of blood)
  2. Platelet count decreased
  3. Palpitations (feelings or sensations that your heart is pounding or racing)
  4. Rash
  5. Depressive symptom
  6. Insomnia (sleeplessness)
  7. Pyrexia (fever)
  8. Renal disorder (kidney disease)
  9. Suicidal ideation
  10. Hepatitis b

What are the existing conditions these people have? *

  1. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 15.15%
  2. Diabetes: 5 people, 15.15%
  3. Type 2 Diabetes: 4 people, 12.12%
  4. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 4 people, 12.12%
  5. High Blood Pressure: 3 people, 9.09%
  6. High Blood Cholesterol: 3 people, 9.09%
  7. Insomnia (sleeplessness): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Ursodeoxycholic acid and Pegintron?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ursodeoxycholic acid and Pegintron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ursodeoxycholic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pegintron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ursodeoxycholic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pegintron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ursodiol and peginterferon alfa-2b (the active ingredients of Ursodeoxycholic acid and Pegintron, respectively), and Ursodeoxycholic acid and Pegintron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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