Casodex and Evista drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Casodex (bicalutamide) and Evista (raloxifene hydrochloride). Common drug interactions include abscess jaw among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Casodex and Evista. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Casodex?

Casodex has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 10,725 Casodex users. Check the latest studies of Casodex.

What is Evista?

Evista has active ingredients of raloxifene hydrochloride. It is often used in osteoporosis. eHealthMe is studying from 25,891 Evista users. Check the latest studies of Evista.

On Jul, 25, 2026

12 people who take Casodex and Evista together, and have interactions are studied.

What are the common drug interactions of Casodex and Evista, by gender? *:

female:

Abscess jaw (tooth abscess or root abscess)
Actinomycosis (infection that causes sores, or abscesses)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia of chronic disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Arthropathy

male:

Anxiety
Pain
Insomnia (sleeplessness)
Intervertebral disc protrusion (spinal disc protrusion)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Lymphadenopathy (disease or enlargement of lymph nodes)
Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)
Pain in jaw
Urinary incontinence (inability to control the flow of urine and involuntary urination)

What are the common drug interactions of Casodex and Evista, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Arthropathy
Balanoposthitis (inflammation of the glands penis and the foreskin)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Benign oesophageal neoplasm (benign (non-cancerous) tumours of the oesophageal)
Bladder diverticulum (pouch like projection in the bladder, by birth or acquired)
Blood testosterone decreased
Bone erosion
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Abdominal pain upper
Abscess jaw (tooth abscess or root abscess)
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone swelling
Cough
Dental fistula
Disability
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dizziness
Dyspepsia (indigestion)

What are the existing conditions these people have? *

Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 10 people, 83.33%
Gynecomastia (enlargement of the gland tissue of the male breast): 10 people, 83.33%
Osteopenia (a condition where bone mineral density is lower than normal): 8 people, 66.67%
Metastases To Bone (cancer spreads to bone): 1 person, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
Bone Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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