Ursodiol and Abilify drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ursodiol (ursodiol) and Abilify (aripiprazole). Common drug interactions include nausea among females and hepatomegaly among males.

The phase IV clinical study analyzes what interactions people have when they take Ursodiol and Abilify. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.

On Jul, 19, 2026

80 people who take Ursodiol and Abilify together, and have interactions are studied.

What are the common drug interactions of Ursodiol and Abilify, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Blood triglycerides increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diabetic complication
Dizziness
Hospitalisation
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Joint injury
Nephritic syndrome (a collection of signs (known as a syndrome) associated with disorders affecting the kidneys, more specifically glomerular disorders)
Obesity (having too much body fat)

male:

Hepatomegaly (abnormal enlargement of the liver)
Anxiety
Drug hypersensitivity
Dry mouth
Eating disorder
Eosinophil count increased
Excessive masturbation
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)

What are the common drug interactions of Ursodiol and Abilify, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Benign renal neoplasm (benign (non-cancerous) tumours of the kidney)
Cholangitis sclerosing (infection and obstruction of bile duct)
Flatulence (flatus expelled through the anus)
Hepatomegaly (abnormal enlargement of the liver)
Hypertension (high blood pressure)
Ascites (accumulation of fluid in the abdominal cavity)
Drug dependence
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Left ventricular dysfunction
Poor quality sleep

30-39:

Cough
Anxiety
Dyspepsia (indigestion)
Vomiting
Weight increased
Abdominal discomfort
Abdominal pain upper
Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
Binge eating (pattern of disordered eating which consists of episodes of uncontrollable eating)
Compulsive sexual behaviour (unable to manage his/her sexual behaviour)

40-49:

Disturbance in attention
Dysfunctional uterine bleeding
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Muscle spasms (muscle contraction)
Renal failure (kidney dysfunction)
Somnolence (a state of near-sleep, a strong desire for sleep)
Vision blurred
Weight decreased
Weight increased
Vaginal haemorrhage (vaginal bleeding)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Pruritus (severe itching of the skin)
Glomerulonephritis chronic (long lasting group of conditions that affect parts of the kidneys called glomeruli)
Nephrogenic anaemia (anaemia due to kidney disease)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Renal haematoma (blood collection in kidney)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephritic syndrome (a collection of signs (known as a syndrome) associated with disorders affecting the kidneys, more specifically glomerular disorders)

60+:

Dysarthria (speech disorder)
Electrolyte imbalance
Fluid retention (an abnormal accumulation of fluid in the blood)
Gait disturbance
Gastrointestinal candidiasis (fungal infection of gastrointestinal tract)
Jaundice cholestatic
Mania (a state of abnormally elevated or irritable mood)
Metastases to liver (cancer spreads to liver)
Metastases to lung (cancer spreads to lung)
Metastases to pleura (cancer spreads to pleura)

What are the existing conditions these people have? *

Stress And Anxiety: 11 people, 13.75%
Pain: 10 people, 12.50%
Cystic Fibrosis (disease of the secretary glands): 10 people, 12.50%
High Blood Cholesterol: 10 people, 12.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 11.25%
Liver Disorder (liver diseases): 7 people, 8.75%
High Blood Pressure: 7 people, 8.75%
Sleep Disorder: 7 people, 8.75%
Gout (uric acid crystals building up in the body): 7 people, 8.75%
Blood Pressure Abnormal: 7 people, 8.75%

* Approximation only. Some reports may have incomplete information.

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