Ursodiol and Cyclobenzaprine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ursodiol (ursodiol) and Cyclobenzaprine hydrochloride (cyclobenzaprine hydrochloride). Common drug interactions include decreased appetite among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Ursodiol and Cyclobenzaprine hydrochloride. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

What is Cyclobenzaprine hydrochloride?

Cyclobenzaprine hydrochloride has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 9,351 Cyclobenzaprine hydrochloride users. Check the latest studies of Cyclobenzaprine hydrochloride.

On Jul, 15, 2026

47 people who take Ursodiol and Cyclobenzaprine hydrochloride together, and have interactions are studied.

Ursodiol and Cyclobenzaprine hydrochloride drug interactions.

What are the common drug interactions of Ursodiol and Cyclobenzaprine Hydrochloride, by gender? *:

female:

Decreased appetite
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disease progression
Dizziness
Drug intolerance (drug sensitivity)
Dry gangrene (diminished blood supply due to vascular problems)
Dry mouth
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)

male:

Diarrhoea
Fatigue (feeling of tiredness)
Influenza
Monoparesis (one limb is very weak, but not completely paralyzed)
Night sweats (sweating in night)
Pyrexia (fever)
Rectal haemorrhage (bleeding from anus)
Thrombosis (formation of a blood clot inside a blood vessel)
Ulcer haemorrhage (bleeding ulcer)
Weight decreased

What are the common drug interactions of Ursodiol and Cyclobenzaprine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Burns second degree
Death
Flushing (the warm, red condition of human skin)
Gait disturbance
Pain in extremity
Uhthoff's phenomenon (heat intolerance)

50-59:

Intertrigo (inflammation (rash) of the body folds (adjacent areas of skin))
Lacrimation increased
Migraine (headache)
Mitral valve calcification (calcium deposit in mitral valve)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain
Photophobia (extreme sensitivity to light)
Pneumonia

60+:

Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Asthenia (weakness)
Bacteraemia (presence of bacteria in the blood)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrointestinal infection (infection of stomach and intestine)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypophagia (reduced food intake)

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 8 people, 17.02%
Primary Immunodeficiency Syndrome: 4 people, 8.51%
Multiple Myeloma (cancer of the plasma cells): 4 people, 8.51%
Immunodeficiency Common Variable: 4 people, 8.51%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 3 people, 6.38%
Infection: 3 people, 6.38%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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