Ursodiol and Yasmin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ursodiol (ursodiol) and Yasmin (drospirenone; ethinyl estradiol). Common drug interactions include injury among females.

The phase IV clinical study analyzes what interactions people have when they take Ursodiol and Yasmin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

What is Yasmin?

Yasmin has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 48,855 Yasmin users. Check the latest studies of Yasmin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

12 people who take Ursodiol and Yasmin together, and have interactions are studied.

What are the common drug interactions of Ursodiol and Yasmin, by gender? *:

female:

Injury
Cholecystitis chronic (long lasting infection of gallbladder)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Abdominal pain upper
Abdominal distension
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Cholecystitis acute (rapid infection of gallbladder)
Depression
Eating disorder
Flatulence (flatus expelled through the anus)

male:

n/a

What are the common drug interactions of Ursodiol and Yasmin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain upper
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Chest pain
Cholecystitis chronic (long lasting infection of gallbladder)
Dyspepsia (indigestion)
Gallbladder disorder
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nausea (feeling of having an urge to vomit)
Pain
Procedural pain

20-29:

Cholecystitis (infection of gallbladder)
Injury
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Vena cava thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart)

30-39:

Injury
Cholecystitis chronic (long lasting infection of gallbladder)
Abdominal tenderness
Biliary colic
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Eating disorder
Emotional distress
Gastric disorder (disease of stomach)

40-49:

Abdominal distension
Anxiety
Biliary colic
Cholecystitis acute (rapid infection of gallbladder)
Diarrhoea
Dyspepsia (indigestion)
Emotional distress
Flatulence (flatus expelled through the anus)
Injury
Nausea (feeling of having an urge to vomit)

50-59:

Gallbladder disorder
Renal failure (kidney dysfunction)
Emotional distress

60+:

Abdominal pain upper
Cholecystitis chronic (long lasting infection of gallbladder)
Diarrhoea
Electrocardiogram qt prolonged
Injury
Multi-organ failure (multisystem organ failure)
Nausea (feeling of having an urge to vomit)
Pain
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Migraine (headache): 4 people, 33.33%
Pain: 3 people, 25.00%
Premenstrual Syndrome: 2 people, 16.67%
Multiple Allergies (allergy to multiple agents): 2 people, 16.67%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 16.67%
Liver Disorder (liver diseases): 2 people, 16.67%
Muscle Spasms (muscle contraction): 1 person, 8.33%
Painful Menstrual Periods: 1 person, 8.33%
Menstruation Irregular: 1 person, 8.33%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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