Ursodiol and Zerbaxa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ursodiol (ursodiol) and Zerbaxa (ceftolozane sulfate; tazobactam sodium). Common drug interactions include pancytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Ursodiol and Zerbaxa. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

What is Zerbaxa?

Zerbaxa has active ingredients of ceftolozane sulfate; tazobactam sodium. eHealthMe is studying from 1,018 Zerbaxa users. Check the latest studies of Zerbaxa.



On Jul, 15, 2026

30 people who take Ursodiol and Zerbaxa together, and have interactions are studied.

Ursodiol and Zerbaxa drug interactions.

What are the common drug interactions of Ursodiol and Zerbaxa, by gender? *:

female:

n/a

male:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Blood creatinine increased
  4. Blood urea increased
  5. Bronchial haemorrhage (bleeding in bronchia)
  6. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  7. Constipation
  8. Cough
  9. Cystic fibrosis (disease of the secretary glands)
  10. Diarrhoea

What are the common drug interactions of Ursodiol and Zerbaxa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Bandaemia (excess of band cells (immature white blood cells) released by the bone marrow into the blood)
  2. Blood creatinine increased
  3. Blood urea increased
  4. Bronchial haemorrhage (bleeding in bronchia)
  5. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  6. Constipation
  7. Cough
  8. Cystic fibrosis (disease of the secretary glands)
  9. Diarrhoea
  10. Dysphagia (a condition in which swallowing is difficult or painful)

40-49:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Confusional state
  4. Cellulitis (infection under the skin)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. High Blood Pressure: 28 people, 93.33%
  2. Pain: 28 people, 93.33%
  3. Fungal Infection: 28 people, 93.33%
  4. Abdominal Pain: 19 people, 63.33%
  5. Cellulitis (infection under the skin): 19 people, 63.33%
  6. Diarrhea: 19 people, 63.33%
  7. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 19 people, 63.33%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 19 people, 63.33%
  9. Fever: 16 people, 53.33%
  10. Cystic Fibrosis (disease of the secretary glands): 10 people, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ursodiol and Zerbaxa?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ursodiol and Zerbaxa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ursodiol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zerbaxa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ursodiol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zerbaxa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ursodiol and ceftolozane sulfate; tazobactam sodium (the active ingredients of Ursodiol and Zerbaxa, respectively), and Ursodiol and Zerbaxa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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