Valacyclovir hydrochloride and Zyvox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valacyclovir hydrochloride (valacyclovir hydrochloride) and Zyvox (linezolid). Common drug interactions include coma among females and transient ischaemic attack among males.

The phase IV clinical study analyzes what interactions people have when they take Valacyclovir hydrochloride and Zyvox. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.

What is Zyvox?

Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.

On Jul, 23, 2026

16 people who take Valacyclovir hydrochloride and Zyvox together, and have interactions are studied.

Valacyclovir hydrochloride and Zyvox drug interactions.

What are the common drug interactions of Valacyclovir Hydrochloride and Zyvox, by gender? *:

female:

Coma (state of unconsciousness lasting more than six hours)
Hypotension (abnormally low blood pressure)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dehydration (dryness resulting from the removal of water)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Oedema (fluid collection in tissue)
Bone marrow failure

male:

Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Cardiac arrest
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Malaise (a feeling of general discomfort or uneasiness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Valacyclovir Hydrochloride and Zyvox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cardiac arrest
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Malaise (a feeling of general discomfort or uneasiness)

60+:

Aplasia (defective development or congenital absence of an organ or tissue)
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dehydration (dryness resulting from the removal of water)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Oedema (fluid collection in tissue)
Bone marrow failure
Candida sepsis (candida in blood stream)
Candidiasis (candidiasis or thrush is a fungal infection)
Gastrointestinal necrosis (destruction of gastrointestinal organ)

What are the existing conditions these people have? *

Acute Leukaemia (blood cancer): 9 people, 56.25%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 25.00%
Hypersensitivity: 2 people, 12.50%
Adjustment Disorder With Anxiety: 2 people, 12.50%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 12.50%
Appetite - Increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 2 people, 12.50%
Bleeding Disorders: 2 people, 12.50%
Fever: 2 people, 12.50%
Fungal Infection: 2 people, 12.50%
Gastric Ph Increased: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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