Valacyclovir and Metaxalone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valacyclovir (valacyclovir hydrochloride) and Metaxalone (metaxalone). Common drug interactions include bronchitis among females and deep vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Valacyclovir and Metaxalone. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

What is Metaxalone?

Metaxalone has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 4,452 Metaxalone users. Check the latest studies of Metaxalone.

On Jul, 11, 2026

89 people who take Valacyclovir and Metaxalone together, and have interactions are studied.

Valacyclovir and Metaxalone drug interactions.

What are the common drug interactions of Valacyclovir and Metaxalone, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Carcinoembryonic antigen increased
Depression
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Dizziness
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Neoplasm malignant (cancer tumour)
Neuropathy peripheral (surface nerve damage)
Osteoporosis (bones weak and more likely to break)
Sinusitis (inflammation of sinus)

male:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Oedema peripheral (superficial swelling)
Dysphonia (speech disorder attributable to a disorder of phonation)
Emotional distress
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Lip swelling
Nausea (feeling of having an urge to vomit)
Pain

What are the common drug interactions of Valacyclovir and Metaxalone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Depression
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Insomnia (sleeplessness)
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)

40-49:

Multiple fractures
Muscle twitching
Nausea (feeling of having an urge to vomit)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Nephropathy (damage to or disease of a kidney)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Renal atrophy (wasting of kidney)
Renal failure (kidney dysfunction)
Rib fracture

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone density decreased
Chronic kidney disease
Emotional distress
Nausea (feeling of having an urge to vomit)
Osteoporosis (bones weak and more likely to break)
Pain
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)

60+:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Oedema peripheral (superficial swelling)
Dysphonia (speech disorder attributable to a disorder of phonation)
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Lip swelling
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Pneumonia

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 20 people, 22.47%
Pain: 16 people, 17.98%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 10.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 8.99%
Immunodeficiency Common Variable: 7 people, 7.87%
Nausea (feeling of having an urge to vomit): 6 people, 6.74%
Inflammation: 6 people, 6.74%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 6.74%
Asthma: 6 people, 6.74%
Stress And Anxiety: 5 people, 5.62%

* Approximation only. Some reports may have incomplete information.

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