Valchlor and Lexapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valchlor (mechlorethamine hydrochloride) and Lexapro (escitalopram oxalate). Common drug interactions include emphysema among females and application site discolouration among males.

The phase IV clinical study analyzes what interactions people have when they take Valchlor and Lexapro. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Valchlor?

Valchlor has active ingredients of mechlorethamine hydrochloride. eHealthMe is studying from 2,539 Valchlor users. Check the latest studies of Valchlor.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

15 people who take Valchlor and Lexapro together, and have interactions are studied.

What are the common drug interactions of Valchlor and Lexapro, by gender? *:

female:

Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Pneumonia
Pulmonary thrombosis (scarring in the lungs)
Application site irritation
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Rash
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin irritation

male:

Application site discolouration
Application site pain
Rash
Skin burning sensation
Skin exfoliation (removal of the oldest dead skin cells)
Skin irritation
Skin reaction
Urticaria (rash of round, red welts on the skin that itch intensely)
Application site hypersensitivity
Application site irritation

What are the common drug interactions of Valchlor and Lexapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Application site pain
Application site discolouration
Erythema (redness of the skin)
Hyperhidrosis (abnormally increased sweating)
Pruritus (severe itching of the skin)
Skin burning sensation
Skin exfoliation (removal of the oldest dead skin cells)
Urticaria (rash of round, red welts on the skin that itch intensely)
Application site irritation
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

What are the existing conditions these people have? *

Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 11 people, 73.33%

* Approximation only. Some reports may have incomplete information.

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