Valcyte and Leflunomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valcyte (valganciclovir hydrochloride) and Leflunomide (leflunomide). Common drug interactions include deafness among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Valcyte and Leflunomide. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Valcyte?

Valcyte has active ingredients of valganciclovir hydrochloride. It is often used in cmv - immunocompromised host. eHealthMe is studying from 6,409 Valcyte users. Check the latest studies of Valcyte.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

On Jul, 10, 2026

24 people who take Valcyte and Leflunomide together, and have interactions are studied.

Valcyte and Leflunomide drug interactions.

What are the common drug interactions of Valcyte and Leflunomide, by gender? *:

female:

Deafness
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Infected skin ulcer
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Pneumonia
Productive cough
Skin ulcer

male:

Chronic kidney disease
Kidney transplant rejection
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Blood calcium decreased
Blood sodium decreased
Cardiac failure congestive
Nephropathy (damage to or disease of a kidney)
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Valcyte and Leflunomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Renal impairment (severely reduced kidney function)
Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
Blighted ovum
Diarrhoea
Pyrexia (fever)
Thrombocytopenia (decrease of platelets in blood)
Chronic kidney disease
Renal failure (kidney dysfunction)

40-49:

n/a

50-59:

n/a

60+:

Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Diarrhoea
Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Thrombocytopenia (decrease of platelets in blood)
Kidney transplant rejection
Pneumonia primary atypical (primary atypical pneumonia which were probably caused by mycoplasma pneumoniae)
Thalamus haemorrhage (bleeding in thalamus)

What are the existing conditions these people have? *

Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 6 people, 25.00%
Inflammation: 4 people, 16.67%
High Blood Cholesterol: 4 people, 16.67%
Immunodeficiency Disorders: 3 people, 12.50%
Depression: 3 people, 12.50%
Cytomegalovirus Infection: 3 people, 12.50%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 8.33%
Prostatomegaly (enlargement of the prostate): 2 people, 8.33%
Neuralgia (pain in one or more nerves): 2 people, 8.33%
Infection: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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