Valium and Moduretic 5-50 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valium (diazepam) and Moduretic 5-50 (amiloride hydrochloride; hydrochlorothiazide). Common drug interactions include confusional state among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Valium and Moduretic 5-50. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

What is Moduretic 5-50?

Moduretic 5-50 has active ingredients of amiloride hydrochloride; hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 3,224 Moduretic 5-50 users. Check the latest studies of Moduretic 5-50.

On Jul, 31, 2026

20 people who take Valium and Moduretic 5-50 together, and have interactions are studied.

Valium and Moduretic 5-50 drug interactions.

What are the common drug interactions of Valium and Moduretic 5-50, by gender? *:

female:

Confusional state
Respiratory tract infection
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hypoxia (low oxygen in tissues)
Productive cough
Blood bilirubin increased
Encephalitis (inflammation of the brain)
Wheezing (a high-pitched whistling sound made while you breath)
Cerebellar infarction (impaired blood circulation to cerebellum)
Gait disturbance

male:

Pain
Abscess (pus)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Angiopathy (generic term for a disease of the blood vessels)
Bedridden
Carotid artery stenosis (narrowing of carotid artery)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dysphasia (language disorder marked by deficiency in the generation of speech)
Dysstasia (difficulty in standing)

What are the common drug interactions of Valium and Moduretic 5-50, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abscess (pus)
Depression
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Pain
Gastroenteritis (inflammation of stomach and intestine)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

40-49:

Flushing (the warm, red condition of human skin)

50-59:

Hallucination, visual (seeing things that aren't there)
Oedema peripheral (superficial swelling)
Paralysis
Proteinuria (presence of protein in the urine)
Therapeutic response unexpected
Wound

60+:

Confusional state
Respiratory tract infection
Cerebellar infarction (impaired blood circulation to cerebellum)
Erythema (redness of the skin)
Gait disturbance
Haematocrit decreased
Oedema peripheral (superficial swelling)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Abdominal pain upper
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

What are the existing conditions these people have? *

Hepatic Neoplasm Malignant (liver cancer): 8 people, 40.00%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 4 people, 20.00%
Osteoporosis (bones weak and more likely to break): 4 people, 20.00%
Type 2 Diabetes: 4 people, 20.00%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 20.00%
Portal Hypertension (increase in the blood pressure within a system of veins called the portal venous system): 4 people, 20.00%
Back Pain: 3 people, 15.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 15.00%
Diarrhea: 3 people, 15.00%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 3 people, 15.00%

* Approximation only. Some reports may have incomplete information.

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