Valium and Purinethol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valium (diazepam) and Purinethol (mercaptopurine). Common drug interactions include eosinophilia among females and chest discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Valium and Purinethol. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

What is Purinethol?

Purinethol has active ingredients of mercaptopurine. It is often used in ulcerative colitis. eHealthMe is studying from 3,810 Purinethol users. Check the latest studies of Purinethol.

On Jul, 31, 2026

13 people who take Valium and Purinethol together, and have interactions are studied.

Valium and Purinethol drug interactions.

What are the common drug interactions of Valium and Purinethol, by gender? *:

female:

Eosinophilia (eosinophil count in the peripheral blood exceeds)
Hepatocellular injury (liver injury)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Asthenia (weakness)
Asthma
Blood cholesterol increased
Blood potassium decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

Chest discomfort
Drug ineffective
Respiratory tract congestion (blockage on respiratory system)
Tonsillitis (inflammation of tonsil)
Urticaria (rash of round, red welts on the skin that itch intensely)
Wheezing (a high-pitched whistling sound made while you breath)
Dyspnoea (difficult or laboured respiration)
Eye swelling
Infusion related reaction
Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Valium and Purinethol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Eosinophilia (eosinophil count in the peripheral blood exceeds)
Hepatocellular injury (liver injury)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Chest discomfort
Dyspnoea (difficult or laboured respiration)
Eye swelling
Infusion related reaction
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)

30-39:

Drug ineffective
Neuropathy peripheral (surface nerve damage)
Tonsillitis (inflammation of tonsil)

40-49:

Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Contusion (a type of hematoma of tissue in which capillaries)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dyskinesia (abnormality or impairment of voluntary movement)
Eye disorder
Frequent bowel movements
Haemoglobin decreased
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)

50-59:

Pharyngolaryngeal pain
Pulmonary congestion (congestion in the lungs)
Dyspnoea (difficult or laboured respiration)
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Hypersensitivity

60+:

Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Asthma
Blood cholesterol increased
Blood potassium decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Injection site pain
Rhinorrhoea (watery mucus discharge from the nose)

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 38.46%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 23.08%
Stomatitis (inflammation of mucous membrane of mouth): 1 person, 7.69%
Pain: 1 person, 7.69%
Nausea (feeling of having an urge to vomit): 1 person, 7.69%
Meningeal Leukaemia (cancer cells have spread from the original (primary) tumour to the meninges (thin layers)): 1 person, 7.69%
Insomnia (sleeplessness): 1 person, 7.69%
Hypotonia (low muscle tone): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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