Valium and Rapamune drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valium (diazepam) and Rapamune (sirolimus). Common drug interactions include kidney transplant rejection among females and diabetic coma among males.

The phase IV clinical study analyzes what interactions people have when they take Valium and Rapamune. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.

On Jul, 22, 2026

29 people who take Valium and Rapamune together, and have interactions are studied.

What are the common drug interactions of Valium and Rapamune, by gender? *:

female:

Kidney transplant rejection
Drug ineffective
Diarrhoea
Hypertension (high blood pressure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Anaemia (lack of blood)
Decreased appetite
Dysgeusia (disorder of the sense of taste)
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphonia (speech disorder attributable to a disorder of phonation)

male:

Diabetic coma
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Haemoglobin decreased
Hypogeusia (reduced ability to taste things (to taste sweet, sour, bitter, or salty substances))
Libido decreased (loss of interest in sex)
Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
Neurological symptom (symptoms of nervous system disease)
Optic atrophy (the loss of a proportion of optic disc nerve fibres)
Optic neuritis (optic nerve inflammation)
Papillitis (inflammation of the optic nerve head)

What are the common drug interactions of Valium and Rapamune, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cardiac failure
Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)

20-29:

Death
Leukopenia (less number of white blood cells in blood)

30-39:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Hypophagia (reduced food intake)
Nausea (feeling of having an urge to vomit)
Weight decreased
Activated partial thromboplastin time prolonged
Blood bilirubin increased
Blood fibrinogen increased
Haemoglobin decreased
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Heart rate increased

40-49:

Diabetic coma
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Blindness
Death
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

Kidney transplant rejection
Blindness
Drug ineffective
Gait disturbance
Neurological symptom (symptoms of nervous system disease)
Visual disturbance
Abdominal discomfort
Blood creatine phosphokinase increased
Blood pressure inadequately controlled
Blood pressure increased

60+:

Headache (pain in head)
Anaemia (lack of blood)
Hypertension (high blood pressure)
Pruritus (severe itching of the skin)
Sinus disorder (disease of sinus)
Swollen tongue (swelling of tongue)
Weight decreased
Drug ineffective
Drug resistance (reduction in effectiveness of a drug)
Herpes zoster

What are the existing conditions these people have? *

Pain: 6 people, 20.69%
Immunodeficiency Disorders: 4 people, 13.79%
High Blood Pressure: 3 people, 10.34%
Insomnia (sleeplessness): 2 people, 6.90%
Depression: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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