Valium and Ryzolt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valium (diazepam) and Ryzolt (tramadol hydrochloride). Common drug interactions include drug dependence among females and drug dependence among males.

The phase IV clinical study analyzes what interactions people have when they take Valium and Ryzolt. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

What is Ryzolt?

Ryzolt has active ingredients of tramadol hydrochloride. eHealthMe is studying from 3,226 Ryzolt users. Check the latest studies of Ryzolt.

On Jul, 13, 2026

18 people who take Valium and Ryzolt together, and have interactions are studied.

What are the common drug interactions of Valium and Ryzolt, by gender? *:

female:

Drug dependence
Overdose
Pain
Abortion spontaneous (naturally occurring miscarriage)
Depression suicidal (suicide depressive disorder)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Emotional distress
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Disability

male:

Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Antisocial behaviour
Death
Disinhibition (loss of inhibition)
Memory impairment
Personality change
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Nerve injury
Substance abuse

What are the common drug interactions of Valium and Ryzolt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abortion spontaneous (naturally occurring miscarriage)
Affective disorder (mental disorder)
Dependence
Depression suicidal (suicide depressive disorder)
Nulliparous (a woman who has never given birth to a viable, or live, infant)
Overdose
Pain
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Allergic colitis (inflammation of the colon due to allergy)
Carotid artery stenosis (narrowing of carotid artery)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chorea (abnormal involuntary movement disorder)
Colitis (inflammation of colon)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

60+:

n/a

What are the existing conditions these people have? *

Pain: 7 people, 38.89%
Muscle Spasms (muscle contraction): 5 people, 27.78%
Intervertebral Disc Degeneration (spinal disc degeneration): 5 people, 27.78%
Limb Injury: 4 people, 22.22%
Breakthrough Pain: 4 people, 22.22%
Lumbar Spinal Stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 1 person, 5.56%
Impaired Gastric Emptying: 1 person, 5.56%
Herniated Nucleus Pulposus (Slipped Disk): 1 person, 5.56%
Common Peroneal Nerve Dysfunction (dysfunction of nerve controlling movement and sensation to the lower leg, foot and toes): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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