Valproic acid and Crixivan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valproic acid (valproic acid) and Crixivan (indinavir sulfate). Common drug interactions include liver fatty among females and grand mal convulsion among males.

The phase IV clinical study analyzes what interactions people have when they take Valproic acid and Crixivan. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Valproic acid?

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.

What is Crixivan?

Crixivan has active ingredients of indinavir sulfate. eHealthMe is studying from 6,312 Crixivan users. Check the latest studies of Crixivan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

26 people who take Valproic acid and Crixivan together, and have interactions are studied.

Valproic acid and Crixivan drug interactions.

What are the common drug interactions of Valproic Acid and Crixivan, by gender? *:

female:

Liver fatty (fat deposition of liver)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Vomiting
Gamma-glutamyltransferase increased
Lactic acidosis (low ph in body tissues)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Acidosis (build-up of carbon dioxide in the blood)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase nos increased

male:

Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haematocrit increased
Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)
Haemoglobin decreased
Haemoglobin increased
Hypoxia (low oxygen in tissues)
Inflammation
Pain
Vascular anomaly
Anaemia (lack of blood)

What are the common drug interactions of Valproic Acid and Crixivan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Asthma
Blood carbon dioxide decreased
Blood lactate dehydrogenase increased
Cushingoid (obesity and weakening of the muscles)
Dyspnoea (difficult or laboured respiration)
Femur fracture
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Haemoglobin decreased
Haemolytic anaemia (anaemia due to haemolysis)

40-49:

Liver fatty (fat deposition of liver)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Vomiting
Gamma-glutamyltransferase increased
Lactic acidosis (low ph in body tissues)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Acidosis (build-up of carbon dioxide in the blood)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase nos increased

50-59:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Gamma-glutamyltransferase increased
Hypokalaemia (low potassium)
Lymphocyte count increased
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Muscle atrophy (a decrease in the mass of the muscle)
Pleural effusion (water on the lungs)
Recurrent cancer (repeated cancer)
Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

n/a

* Approximation only. Some reports may have incomplete information.

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