Valtrex and Cayston drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valtrex (valacyclovir hydrochloride) and Cayston (aztreonam). Common drug interactions include chronic obstructive pulmonary disease among females.

The phase IV clinical study analyzes what interactions people have when they take Valtrex and Cayston. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 39,999 Valtrex users. Check the latest studies of Valtrex.

What is Cayston?

Cayston has active ingredients of aztreonam. It is often used in cystic fibrosis. eHealthMe is studying from 5,310 Cayston users. Check the latest studies of Cayston.



On Aug, 12, 2026

15 people who take Valtrex and Cayston together, and have interactions are studied.

Valtrex and Cayston drug interactions.

What are the common drug interactions of Valtrex and Cayston, by gender? *:

female:

  1. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  2. Dyspnoea (difficult or laboured respiration)
  3. Scar
  4. Blood pressure decreased
  5. Dyspnoea exertional (breathlessness or shortness of breath)
  6. Fatigue (feeling of tiredness)
  7. Influenza a virus test positive
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Respiratory rate increased (excess breathing rate/min)
  10. Rhonchi (abnormal breath sounds)

male:

n/a

What are the common drug interactions of Valtrex and Cayston, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Blood pressure decreased
  2. Cough
  3. Decreased appetite
  4. Dyspnoea exertional (breathlessness or shortness of breath)
  5. Fatigue (feeling of tiredness)
  6. Forced expiratory volume decreased (decreased lung expired air volume)
  7. Heart rate increased
  8. Influenza a virus test positive
  9. Respiratory rate increased (excess breathing rate/min)
  10. Rhonchi (abnormal breath sounds)

30-39:

  1. Abdominal pain upper
  2. Blood pressure increased
  3. Body temperature decreased
  4. Chest discomfort
  5. Cough
  6. Decreased appetite
  7. Distal intestinal obstruction syndrome (blockage of the intestines by thickened stool and occurs in individuals with cystic fibrosis)
  8. Dizziness
  9. Forced expiratory volume decreased (decreased lung expired air volume)
  10. Hearing impaired

40-49:

  1. Depression
  2. Device dislocation
  3. Dyspnoea (difficult or laboured respiration)
  4. Fungal infection
  5. Insomnia (sleeplessness)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Migraine (headache)
  8. Muscular weakness (muscle weakness)
  9. Pain
  10. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)

50-59:

n/a

60+:

  1. Acne (skin problems that cause pimples)
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Dyspnoea (difficult or laboured respiration)
  4. Scar
  5. Weight decreased

What are the existing conditions these people have? *

  1. Hypersensitivity: 3 people, 20.00%
  2. Sleep Disorder: 2 people, 13.33%
  3. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 2 people, 13.33%
  4. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.67%
  5. Obstructive Airways Disorder (a progressive disease that makes it hard to breathe): 1 person, 6.67%
  6. Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 1 person, 6.67%
  7. Cystic Fibrosis Related Diabetes: 1 person, 6.67%
  8. Cystic Fibrosis Lung (fibrosis with cyst in the lung): 1 person, 6.67%
  9. Coughing Up Blood: 1 person, 6.67%
  10. Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Valtrex and Cayston?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Valtrex and Cayston:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valtrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cayston:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valtrex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cayston and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on valacyclovir hydrochloride and aztreonam (the active ingredients of Valtrex and Cayston, respectively), and Valtrex and Cayston (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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