Valtrex and Geodon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valtrex (valacyclovir hydrochloride) and Geodon (ziprasidone hydrochloride). Common drug interactions include diabetes mellitus inadequate control among females and somnolence among males.

The phase IV clinical study analyzes what interactions people have when they take Valtrex and Geodon. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 40,000 Valtrex users. Check the latest studies of Valtrex.

What is Geodon?

Geodon has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 19,505 Geodon users. Check the latest studies of Geodon.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

83 people who take Valtrex and Geodon together, and have interactions are studied.

What are the common drug interactions of Valtrex and Geodon, by gender? *:

female:

Diabetes mellitus inadequate control
Dysgraphia (impaired ability to learn to write)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Headache (pain in head)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hyperglycaemia (high blood sugar)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Irritability
Localised infection (infection at the single location)
Loss of consciousness

male:

Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased
Dyspepsia (indigestion)
Hypoaesthesia (reduced sense of touch or sensation)
Memory impairment
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Suicide attempt
Abdominal pain upper
Adverse event

What are the common drug interactions of Valtrex and Geodon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pancreatitis (inflammation of pancreas)
Pancreatitis acute (sudden inflammation of pancreas)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Abdominal pain
Anxiety
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
Gallbladder disorder
Injury

30-39:

Suicidal ideation
Obesity (having too much body fat)
Type 2 diabetes mellitus
Blood cholesterol increased
Hyperlipidaemia (presence of excess lipids in the blood)
Weight increased
Dyslipidaemia (abnormal amount of lipids)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Anxiety
Death

40-49:

Anxiety
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Discomfort
Dysphagia (a condition in which swallowing is difficult or painful)
Blood cholesterol increased
Weight increased
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Oesophageal stenosis (narrowing of oesophagus)
Pulmonary embolism (blockage of the main artery of the lung)
Aphasia (damage to the parts of the brain that control language)

50-59:

Tremor (trembling or shaking movements in one or more parts of your body)
Type 2 diabetes mellitus
Upper limb fracture
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug ineffective
Death
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Anxiety

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Somnolence (a state of near-sleep, a strong desire for sleep)
Fatigue (feeling of tiredness)
Gait disturbance
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Insomnia (sleeplessness)
Irritability
Loss of consciousness
Mobility decreased (ability to move is reduced)

What are the existing conditions these people have? *

Depression: 22 people, 26.51%
Stress And Anxiety: 13 people, 15.66%
Sleep Disorder: 10 people, 12.05%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 8.43%
High Blood Cholesterol: 7 people, 8.43%
Hypersensitivity: 5 people, 6.02%
Headache (pain in head): 5 people, 6.02%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 6.02%
Asthma: 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

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