Valtrex and Milk thistle drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valtrex (valacyclovir hydrochloride) and Milk thistle (milk thistle). Common drug interactions include dizziness among females and adverse drug reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Valtrex and Milk thistle. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 39,999 Valtrex users. Check the latest studies of Valtrex.

What is Milk thistle?

Milk thistle has active ingredients of milk thistle. It is often used in fatty liver. eHealthMe is studying from 5,057 Milk thistle users. Check the latest studies of Milk thistle.

On Jul, 11, 2026

42 people who take Valtrex and Milk thistle together, and have interactions are studied.

Valtrex and Milk thistle drug interactions.

What are the common drug interactions of Valtrex and Milk Thistle, by gender? *:

female:

Dizziness
Dry mouth
Dry skin
Dysuria (painful or difficult urination)
Feeling cold
Fibromyalgia (a long-term condition which causes pain all over the body)
Flushing (the warm, red condition of human skin)
Fracture
Gallbladder disorder
Head injury

male:

Adverse drug reaction
Adverse event
Burning sensation
Cardiac disorder
Chest discomfort
Chronic lymphocytic leukaemia recurrent (repeated cancer of blood cells known as lymphocytes)
Cough
Diarrhoea
Drug hypersensitivity
Drug intolerance (drug sensitivity)

What are the common drug interactions of Valtrex and Milk Thistle, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Kawasaki's disease (an autoimmune disease in which the medium-sized blood vessels throughout the body become inflamed)
Loss of consciousness
Pneumonia

40-49:

Dyspepsia (indigestion)
Lacrimation increased

50-59:

Insomnia (sleeplessness)
Mitochondrial toxicity (a condition in which the mitochondria of a body's cells become damaged or decline significantly in number;)
Mobility decreased (ability to move is reduced)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Neuropathy peripheral (surface nerve damage)
Overdose
Pain
Pain in extremity

60+:

Back pain
Arthralgia (joint pain)
Nausea (feeling of having an urge to vomit)
Neck pain
Rash
Sinus headache (headache caused by sinus infections)
Vaginal haemorrhage (vaginal bleeding)
Abdominal abscess (collection of pus in abdomen)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 30.95%
Stress And Anxiety: 4 people, 9.52%
Immunodeficiency Common Variable: 4 people, 9.52%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.14%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.14%
High Blood Cholesterol: 3 people, 7.14%
Herpes Zoster: 3 people, 7.14%
Herpes Virus Infection: 3 people, 7.14%
Depression: 3 people, 7.14%
Constipation: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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