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Valtrex and Topicort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Valtrex (valacyclovir hydrochloride) and Topicort (desoximetasone). Common drug interactions include acute left ventricular failure among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Valtrex and Topicort. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 39,999 Valtrex users. Check the latest studies of Valtrex.

What is Topicort?

Topicort has active ingredients of desoximetasone. eHealthMe is studying from 3,423 Topicort users. Check the latest studies of Topicort.

On Jul, 15, 2026

20 people who take Valtrex and Topicort together, and have interactions are studied.

Valtrex and Topicort drug interactions.

What are the common drug interactions of Valtrex and Topicort, by gender? *:

female:

  1. Acute left ventricular failure (heart attack)
  2. Acute respiratory failure
  3. Chronic kidney disease
  4. Injection site haemorrhage (bleeding from injection site)
  5. Acne (skin problems that cause pimples)
  6. Blood bilirubin increased
  7. Blood cholesterol decreased
  8. Blood triglycerides increased
  9. Death
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

  1. Depression
  2. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  3. Pain
  4. Skin ulcer
  5. Vomiting
  6. Dry skin
  7. Ulcer

What are the common drug interactions of Valtrex and Topicort, by age (0-1 to 60+)? *:

0-1:

  1. Dermatillomania (skin picking disorders)
  2. Scar

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Headache (pain in head)
  2. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  3. Dehydration (dryness resulting from the removal of water)
  4. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  5. Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
  6. Nausea (feeling of having an urge to vomit)

40-49:

  1. Acne (skin problems that cause pimples)
  2. Blood bilirubin increased
  3. Blood cholesterol decreased
  4. Blood triglycerides increased
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Headache (pain in head)
  7. Low density lipoprotein increased (cholesterol increased in blood)
  8. Mean cell haemoglobin increased (more than normal haemoglobin per red blood cell in a sample of blood)
  9. Memory impairment
  10. Onychoclasis (breaking of the nails)

50-59:

  1. Nausea (feeling of having an urge to vomit)
  2. Injection site haemorrhage (bleeding from injection site)
  3. Injection site bruising
  4. Rash
  5. Injection site pain
  6. Abdominal pain upper
  7. Dizziness
  8. Feeling cold
  9. Headache (pain in head)
  10. Hyperhidrosis (abnormally increased sweating)

60+:

  1. Death
  2. Anaemia (lack of blood)
  3. Asthenia (weakness)
  4. Drug hypersensitivity
  5. Dry eye (lack of adequate tears)
  6. Pleural effusion (water on the lungs)
  7. Sepsis syndrome (a clinical condition of blood infection)
  8. Thrombocytopenia (decrease of platelets in blood)
  9. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  10. Urinary tract infection

What are the existing conditions these people have? *

  1. Pain: 5 people, 25.00%
  2. Asthma: 5 people, 25.00%
  3. Psoriasis (immune-mediated disease that affects the skin): 5 people, 25.00%
  4. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 4 people, 20.00%
  5. Nausea (feeling of having an urge to vomit): 4 people, 20.00%
  6. Infection: 3 people, 15.00%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.00%
  8. Rickets (softening of bones): 3 people, 15.00%
  9. Constipation: 3 people, 15.00%
  10. Seasonal Allergy (allergic condition due to certain season): 3 people, 15.00%

* Approximation only. Some reports may have incomplete information.

Do you take Valtrex and Topicort?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Valtrex and Topicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valtrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Topicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valtrex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Topicort and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on valacyclovir hydrochloride and desoximetasone (the active ingredients of Valtrex and Topicort, respectively), and Valtrex and Topicort (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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