Vancomycin hcl and B12 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hcl (vancomycin hydrochloride) and B12 (cobalamin). Common drug interactions include diarrhoea among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hcl and B12. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hcl?

Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is often used in clostridium difficile colitis. eHealthMe is studying from 6,530 Vancomycin hcl users. Check the latest studies of Vancomycin hcl.

What is B12?

B12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,894 B12 users. Check the latest studies of B12.



On Jul, 12, 2026

47 people who take Vancomycin hcl and B12 together, and have interactions are studied.

Vancomycin hcl and B12 drug interactions.

What are the common drug interactions of Vancomycin Hcl and B12, by gender? *:

female:

  1. Diarrhoea
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Injection site mass
  4. Staphylococcal infection (an infection with staphylococcus bacteria)
  5. Asthenia (weakness)
  6. Pneumonia
  7. Surgery
  8. Antibiotic level above therapeutic
  9. Blood creatinine increased
  10. Anal fissure

male:

  1. Anxiety
  2. Diarrhoea
  3. Cardiac arrest
  4. Drug resistance (reduction in effectiveness of a drug)
  5. Immunodeficiency
  6. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  7. Respiratory failure (inadequate gas exchange by the respiratory system)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  10. Deafness unilateral

What are the common drug interactions of Vancomycin Hcl and B12, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Blood pressure increased
  2. Galactorrhoea (secretion of breast milk in men)
  3. Heart rate increased
  4. Suicidal ideation

30-39:

n/a

40-49:

  1. Drug resistance (reduction in effectiveness of a drug)
  2. Foot fracture
  3. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  4. Malaise (a feeling of general discomfort or uneasiness)

50-59:

  1. Colitis (inflammation of colon)
  2. Diarrhoea
  3. Hypophysitis (inflammation of the pituitary gland)
  4. Immune thrombocytopenic purpura (destruction of blood platelets due to the presence of antiplatelet auto antibodies)
  5. Nausea (feeling of having an urge to vomit)
  6. Neuropathy peripheral (surface nerve damage)

60+:

  1. Diarrhoea
  2. Anxiety
  3. Injection site mass
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Staphylococcal infection (an infection with staphylococcus bacteria)
  6. Antibiotic level above therapeutic
  7. Blood creatinine increased
  8. Cardiac arrest
  9. Immunodeficiency
  10. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 12 people, 25.53%
  2. Pain: 9 people, 19.15%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 19.15%
  4. High Blood Cholesterol: 8 people, 17.02%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 12.77%
  6. Constipation: 5 people, 10.64%
  7. Dyspnea (difficult or laboured breathing): 5 people, 10.64%
  8. Depression: 4 people, 8.51%
  9. Dizziness: 4 people, 8.51%
  10. Heart Rate Irregular: 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

Do you take Vancomycin hcl and B12?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vancomycin hcl and B12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vancomycin hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of B12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin hcl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between B12 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on vancomycin hydrochloride and cobalamin (the active ingredients of Vancomycin hcl and B12, respectively), and Vancomycin hcl and B12 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: