Vancomycin hcl and Kayexalate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hcl (vancomycin hydrochloride) and Kayexalate (sodium polystyrene sulfonate). Common drug interactions include hepatitis toxic among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hcl and Kayexalate. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hcl?

Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is often used in clostridium difficile colitis. eHealthMe is studying from 6,530 Vancomycin hcl users. Check the latest studies of Vancomycin hcl.

What is Kayexalate?

Kayexalate has active ingredients of sodium polystyrene sulfonate. eHealthMe is studying from 5,004 Kayexalate users. Check the latest studies of Kayexalate.



On Aug, 05, 2026

13 people who take Vancomycin hcl and Kayexalate together, and have interactions are studied.

Vancomycin hcl and Kayexalate drug interactions.

What are the common drug interactions of Vancomycin Hcl and Kayexalate, by gender? *:

female:

  1. Hepatitis toxic

male:

  1. Cardiac failure congestive
  2. Cerebral haemorrhage (bleeding within the brain)
  3. Electrolyte imbalance
  4. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  5. Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
  6. Haemorrhagic cyst (bleeding cyst)
  7. Hepatic cyst
  8. Hyperkalaemia (damage to or disease of the kidney)
  9. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  10. Hypotension (abnormally low blood pressure)

What are the common drug interactions of Vancomycin Hcl and Kayexalate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain
  2. Angiopathy (generic term for a disease of the blood vessels)
  3. Cardiac arrest
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  6. Electrolyte imbalance
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. Haemorrhagic cyst (bleeding cyst)
  9. Hepatic cyst
  10. Hyperkalaemia (damage to or disease of the kidney)

50-59:

  1. Balance disorder
  2. Vestibular disorder (disorders of the body's balance (vestibular) system in the inner ear)

60+:

  1. Cardiac failure congestive
  2. Cerebral haemorrhage (bleeding within the brain)
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  5. Generalised oedema (swelling all over the body)
  6. Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
  7. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  8. Large intestinal ulcer
  9. Lethargy (tiredness)
  10. Livedo reticularis (a lace-like purplish discoloration of the skin)

What are the existing conditions these people have? *

  1. Pain: 2 people, 15.38%
  2. Type 1 Diabetes: 1 person, 7.69%
  3. Pneumonia Staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus): 1 person, 7.69%
  4. Hypotension (abnormally low blood pressure): 1 person, 7.69%
  5. Hyperkalemia (damage to or disease of the kidney): 1 person, 7.69%
  6. High Blood Pressure: 1 person, 7.69%
  7. Dry Eyes (lack of adequate tears): 1 person, 7.69%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 7.69%
  9. Constipation: 1 person, 7.69%
  10. Chronic Renal Failure (kidney failure): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vancomycin hcl and Kayexalate:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vancomycin hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kayexalate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin hcl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kayexalate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on vancomycin hydrochloride and sodium polystyrene sulfonate (the active ingredients of Vancomycin hcl and Kayexalate, respectively), and Vancomycin hcl and Kayexalate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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