Vancomycin hydrochloride and Clonidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hydrochloride (vancomycin hydrochloride) and Clonidine (clonidine). Common drug interactions include white blood cell count increased among females and renal tubular necrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hydrochloride and Clonidine. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hydrochloride?

Vancomycin hydrochloride has active ingredients of vancomycin hydrochloride. It is often used in mrsa infection. eHealthMe is studying from 8,399 Vancomycin hydrochloride users. Check the latest studies of Vancomycin hydrochloride.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

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eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

65 people who take Vancomycin hydrochloride and Clonidine together, and have interactions are studied.

Vancomycin hydrochloride and Clonidine drug interactions.

What are the common drug interactions of Vancomycin Hydrochloride and Clonidine, by gender? *:

female:

White blood cell count increased
Acute respiratory failure
Anaemia (lack of blood)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug hypersensitivity
Klebsiella infection
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Thrombocytopenia (decrease of platelets in blood)
Abdominal pain upper

male:

Renal tubular necrosis (death of kidney tubules)
Syncope (loss of consciousness with an inability to maintain postural tone)
Hypotension (abnormally low blood pressure)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Immune thrombocytopenic purpura (destruction of blood platelets due to the presence of antiplatelet auto antibodies)
Haemoglobin decreased
Hypokalaemia (low potassium)
Lymphocyte count decreased
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Protein urine present

What are the common drug interactions of Vancomycin Hydrochloride and Clonidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Drug ineffective
Linear iga disease (a rare, idiopathic or drug-induced autoimmune blistering disease of skin)
Pruritus (severe itching of the skin)
Bradycardia (abnormally slow heart action)
Hepatocellular injury (liver injury)
Hyperthermia (body temperature greatly above normal)
Hypotension (abnormally low blood pressure)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Bone pain
Diarrhoea

10-19:

Atrioventricular block first degree (heart block first degree)
Electrocardiogram pr prolongation
Fall
Head injury
Red man syndrome (a reaction to the drug vancomycin)

20-29:

Aphasia (damage to the parts of the brain that control language)
Chronic kidney disease
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dysarthria (speech disorder)
Dyskinesia (abnormality or impairment of voluntary movement)
Pruritus (severe itching of the skin)
Renal failure (kidney dysfunction)

30-39:

Abdominal distension
Granulocyte count increased
Haemoglobin decreased
Lymphocyte count decreased
Postoperative wound complication
White blood cell count increased
Oxygen saturation decreased
Respiratory rate increased (excess breathing rate/min)
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)

40-49:

Blood bilirubin increased
Deafness neurosensory
Balance disorder
Bilirubin conjugated increased
C-reactive protein increased
Confusional state
Deafness unilateral
Diarrhoea
Haemoglobin decreased
Hemiplegia (paralysis of one side of the body)

50-59:

Overdose
Palpitations (feelings or sensations that your heart is pounding or racing)
Protein urine present
Sleep disorder
Wound complication
Abnormal clotting factor
Acute stress disorder
Blindness
Cellulitis (infection under the skin)
Coagulation factor deficiency (lack of clotting substance in blood)

60+:

Renal failure acute (rapid kidney dysfunction)
Syncope (loss of consciousness with an inability to maintain postural tone)
Blood glucose increased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Klebsiella infection
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pleural effusion (water on the lungs)
Brain injury
C-reactive protein increased

What are the existing conditions these people have? *

Pain: 19 people, 29.23%
Infection: 12 people, 18.46%
Diabetes: 9 people, 13.85%
Itching: 8 people, 12.31%
Sedation: 7 people, 10.77%
Electrolyte Imbalance: 7 people, 10.77%
Rashes (redness): 7 people, 10.77%
Urination - Excessive Volume: 6 people, 9.23%
Constipation: 6 people, 9.23%
Joint Pain: 5 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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