Vancomycin hydrochloride and Valacyclovir hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin hydrochloride (vancomycin hydrochloride) and Valacyclovir hydrochloride (valacyclovir hydrochloride). Common drug interactions include diarrhoea among females and white blood cell count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin hydrochloride and Valacyclovir hydrochloride. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin hydrochloride?

Vancomycin hydrochloride has active ingredients of vancomycin hydrochloride. It is often used in mrsa infection. eHealthMe is studying from 8,399 Vancomycin hydrochloride users. Check the latest studies of Vancomycin hydrochloride.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.



On Jul, 07, 2026

30 people who take Vancomycin hydrochloride and Valacyclovir hydrochloride together, and have interactions are studied.

Vancomycin hydrochloride and Valacyclovir hydrochloride drug interactions.

What are the common drug interactions of Vancomycin Hydrochloride and Valacyclovir Hydrochloride, by gender? *:

female:

  1. Diarrhoea
  2. Death
  3. Salmonellosis (an infection with salmonella bacteria)
  4. Chest discomfort
  5. Hepatic failure (liver failure)
  6. Pneumonia
  7. Pyrexia (fever)
  8. Rash
  9. Renal impairment (severely reduced kidney function)
  10. Respiratory failure (inadequate gas exchange by the respiratory system)

male:

  1. White blood cell count decreased
  2. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  3. Infusion related reaction
  4. Nephropathy toxic (damage to kidney due to toxins)
  5. Oedema peripheral (superficial swelling)
  6. Pulmonary oedema (fluid accumulation in the lungs)
  7. Pyrexia (fever)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Weight increased
  10. Interstitial lung disease

What are the common drug interactions of Vancomycin Hydrochloride and Valacyclovir Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  2. Mucosal inflammation (infection of mucous membrane)

10-19:

  1. Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
  2. Brain abscess
  3. Cystitis haemorrhagic (blood in the urine and painful voiding)
  4. Dyspnoea (difficult or laboured respiration)
  5. Fluid retention (an abnormal accumulation of fluid in the blood)
  6. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  7. Hypertension (high blood pressure)
  8. Joint swelling
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  10. Platelet count decreased

20-29:

  1. Arrhythmia (irregular heartbeat)
  2. Death
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Venoocclusive liver disease (small veins in the liver are obstructed)

30-39:

  1. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  2. Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
  3. Death

40-49:

n/a

50-59:

  1. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  2. Hypervolaemia (abnormally increased volume of blood)
  3. Hypotension (abnormally low blood pressure)
  4. Nephropathy toxic (damage to kidney due to toxins)
  5. Pulmonary oedema (fluid accumulation in the lungs)
  6. Pyrexia (fever)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Weight increased
  9. Arthropathy
  10. Fatigue (feeling of tiredness)

60+:

  1. White blood cell count decreased
  2. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  3. Hypokalaemia (low potassium)
  4. Infusion related reaction
  5. Oedema peripheral (superficial swelling)
  6. Pyrexia (fever)
  7. Rash
  8. Renal impairment (severely reduced kidney function)
  9. Interstitial lung disease
  10. Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 16.67%
  2. Multiple Myeloma (cancer of the plasma cells): 5 people, 16.67%
  3. Bone Marrow Conditioning Regimen: 4 people, 13.33%
  4. High Blood Pressure: 4 people, 13.33%
  5. Depression: 3 people, 10.00%
  6. Constipation: 3 people, 10.00%
  7. Nausea And Vomiting: 3 people, 10.00%
  8. Nausea (feeling of having an urge to vomit): 3 people, 10.00%
  9. Aspergillosis (an infection caused by a fungus called aspergillus): 3 people, 10.00%
  10. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Vancomycin hydrochloride and Valacyclovir hydrochloride?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vancomycin hydrochloride and Valacyclovir hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vancomycin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valacyclovir hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valacyclovir hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on vancomycin hydrochloride and valacyclovir hydrochloride (the active ingredients of Vancomycin hydrochloride and Valacyclovir hydrochloride, respectively), and Vancomycin hydrochloride and Valacyclovir hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: