Vancomycin and Ultram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vancomycin (vancomycin) and Ultram (tramadol hydrochloride). Common drug interactions include osteopenia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Vancomycin and Ultram. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.

On Jul, 31, 2026

67 people who take Vancomycin and Ultram together, and have interactions are studied.

Vancomycin and Ultram drug interactions.

What are the common drug interactions of Vancomycin and Ultram, by gender? *:

female:

Osteopenia (a condition where bone mineral density is lower than normal)
Pain in extremity
Proteinuria (presence of protein in the urine)
Pyrexia (fever)
Renal tubular necrosis (death of kidney tubules)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
Staphylococcal infection (an infection with staphylococcus bacteria)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Streptococcal infection

male:

Chronic kidney disease
Death
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Nephrogenic anaemia (anaemia due to kidney disease)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Scrotal abscess (pus in scrotum)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Arteriovenous fistula
Anion gap increased
Back disorder

What are the common drug interactions of Vancomycin and Ultram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arteriovenous fistula
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Infection
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Sepsis (a severe blood infection that can lead to organ failure and death)

30-39:

Chronic kidney disease
Dyspepsia (indigestion)
Gastritis (inflammation of stomach)
Death
Endocarditis (inflammation in heart muscle)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Sepsis (a severe blood infection that can lead to organ failure and death)

40-49:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Chronic kidney disease
Renal injury (kidney injury)
Anal abscess
Emotional distress
Genital abscess (build up of pus in genital)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Nerve injury
Renal failure (kidney dysfunction)
Scar

50-59:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal failure (kidney dysfunction)
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Sepsis (a severe blood infection that can lead to organ failure and death)
Anal abscess
Cardiac arrest
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Emotional distress
Genital abscess (build up of pus in genital)

60+:

Chronic kidney disease
Death
Anaemia (lack of blood)
Anal abscess
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anion gap increased
Anxiety
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back disorder
Bone density decreased

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 50 people, 74.63%
Infection: 43 people, 64.18%
High Blood Cholesterol: 33 people, 49.25%
Blood Pressure Abnormal: 25 people, 37.31%
Depression: 24 people, 35.82%
High Blood Pressure: 21 people, 31.34%
Cardiac Disorder: 21 people, 31.34%
Renal Disorder (kidney disease): 14 people, 20.90%
Oedema (fluid collection in tissue): 14 people, 20.90%
Hypersensitivity: 12 people, 17.91%

* Approximation only. Some reports may have incomplete information.

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