Vascepa and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vascepa (icosapent ethyl) and Premarin (estrogens, conjugated). Common drug interactions include urinary tract infection among females.

The phase IV clinical study analyzes what interactions people have when they take Vascepa and Premarin. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Vascepa?

Vascepa has active ingredients of icosapent ethyl. It is often used in high blood cholesterol. eHealthMe is studying from 5,894 Vascepa users. Check the latest studies of Vascepa.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 21, 2026

27 people who take Vascepa and Premarin together, and have interactions are studied.

What are the common drug interactions of Vascepa and Premarin, by gender? *:

female:

Urinary tract infection
Arthralgia (joint pain)
Pneumonia
Wound infection
Alopecia (absence of hair from areas of the body)
Ear infection
Intestinal obstruction
Pyrexia (fever)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety

male:

n/a

What are the common drug interactions of Vascepa and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Catheter site infection (infection at the site of insertion)
Impaired healing
Muscle spasms (muscle contraction)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Urinary tract infection
Wound infection
Chronic kidney disease
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nephrogenic anaemia (anaemia due to kidney disease)
Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)

50-59:

Ear infection
Intestinal obstruction
Pyrexia (fever)
Urinary tract infection
Erythema (redness of the skin)
Rash

60+:

Arthralgia (joint pain)
Myalgia (muscle pain)
Breast tenderness
Oropharyngeal pain
Breast cancer
Corneal abrasion (loss of the surface of cornea)
Eructation (release of gas from the digestive tract)
Hyperhidrosis (abnormally increased sweating)
Kidney infection
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Pain: 6 people, 22.22%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 14.81%
Thyroid Diseases: 3 people, 11.11%
Fatigue (feeling of tiredness): 3 people, 11.11%
Gait Disturbance: 3 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
High Blood Pressure: 3 people, 11.11%
Bladder Disorder: 3 people, 11.11%
Muscle Spasms (muscle contraction): 3 people, 11.11%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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