Vectibix and Oxycontin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vectibix (panitumumab) and Oxycontin (oxycodone hydrochloride). Common drug interactions include febrile neutropenia among females and decreased appetite among males.
The phase IV clinical study analyzes what interactions people have when they take Vectibix and Oxycontin. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.
What is Vectibix?
Vectibix has active ingredients of panitumumab. eHealthMe is studying from 8,945 Vectibix users. Check the latest studies of Vectibix.
What is Oxycontin?
Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.
29 people who take Vectibix and Oxycontin together, and have interactions are studied.

What are the common drug interactions of Vectibix and Oxycontin, by gender? *:
female:
- Febrile neutropenia (fever with reduced white blood cells)
- Abdominal discomfort
- Abdominal pain
- Anxiety
- Blood potassium decreased
- General physical health deterioration (weak health status)
- Hyperhidrosis (abnormally increased sweating)
- Muscle spasms (muscle contraction)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
male:
- Decreased appetite
- Abdominal pain
- Tension (the act or process of stretching something tight)
- Loss of consciousness
- Arrhythmia (irregular heartbeat)
- Ascites (accumulation of fluid in the abdominal cavity)
- Blood magnesium decreased
- Cardiac failure
- Diarrhoea
- Disease progression
What are the common drug interactions of Vectibix and Oxycontin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain
- Anxiety
- Blood potassium decreased
- General physical health deterioration (weak health status)
- Hyperhidrosis (abnormally increased sweating)
- Muscle spasms (muscle contraction)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Infusion related reaction
- Hypophagia (reduced food intake)
- Malaise (a feeling of general discomfort or uneasiness)
50-59:
- Abdominal pain
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Febrile neutropenia (fever with reduced white blood cells)
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Hyperammonaemia
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Platelet count decreased
- Pneumonia
- Renal tubular disorder (disease of kidney tubules)
- Sepsis (a severe blood infection that can lead to organ failure and death)
60+:
- Febrile neutropenia (fever with reduced white blood cells)
- Abdominal discomfort
- Chest pain
- Chills (felling of cold)
- Disinhibition (loss of inhibition)
- Dysphoria (generalized dissatisfaction with life)
- Leukopenia (less number of white blood cells in blood)
- Nausea (feeling of having an urge to vomit)
- Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
- Tension (the act or process of stretching something tight)
What are the existing conditions these people have? *
- Colon Cancer: 16 people, 55.17%
- Rectal Cancer (cancer of rectum): 4 people, 13.79%
- Rectal Cancer Recurrent (reoccurrence of rectum cancer): 3 people, 10.34%
- Insomnia (sleeplessness): 2 people, 6.90%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 6.90%
- High Blood Pressure: 2 people, 6.90%
- Constipation: 2 people, 6.90%
- Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 6.90%
- Cancer Pain: 2 people, 6.90%
* Approximation only. Some reports may have incomplete information.
Do you take Vectibix and Oxycontin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Vectibix and Oxycontin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vectibix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Oxycontin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vectibix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oxycontin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on panitumumab and oxycodone hydrochloride (the active ingredients of Vectibix and Oxycontin, respectively), and Vectibix and Oxycontin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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