Esidrix and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Esidrix (hydrochlorothiazide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Norvasc, and have Dementia alzheimer's type.

The phase IV clinical study analyzes which people have Stroke when taking Esidrix. It is created by eHealthMe based on reports of 1,831 people who have side effects when taking Esidrix from the FDA, and is updated regularly.

What is Esidrix?

Esidrix has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 1,846 Esidrix users. Check the latest studies of Esidrix.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,311 drugs and 3,035 conditions by eHealthMe. Check the latest studies of Stroke.



On Aug, 09, 2026

1,831 people reported to have side effects when taking Esidrix.
Among them, 26 people (1.42%) have Stroke.

Could Esidrix cause Stroke?

Among these 26 people:

How long have people been on Esidrix when they have Stroke? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Stroke when taking Esidrix? *

  • female: 46.15 %
  • male: 53.85 %

What is the age of people who have Stroke when taking Esidrix? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 37.5 %
  • 60+: 62.5 %

What are other drugs people take besides Esidrix? *

  1. Norvasc: 5 people, 19.23%
  2. Aspirin: 4 people, 15.38%
  3. Furosemide: 3 people, 11.54%
  4. Vioxx: 3 people, 11.54%
  5. Singulair: 3 people, 11.54%
  6. Lopressor: 3 people, 11.54%
  7. Lipitor: 2 people, 7.69%
  8. Verelan: 2 people, 7.69%
  9. Glucophage: 2 people, 7.69%
  10. Amlodipine: 2 people, 7.69%

What are other side effects people have besides Stroke? *

  1. Dyspnea (difficult or laboured breathing): 5 people, 19.23%
  2. Haemoglobin Decreased: 3 people, 11.54%
  3. Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 3 people, 11.54%
  4. Headache (pain in head): 3 people, 11.54%
  5. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 11.54%
  6. Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 3 people, 11.54%
  7. Bone Marrow Disorder: 3 people, 11.54%
  8. Atrioventricular Block Second Degree (heart block second degree): 3 people, 11.54%
  9. Atrioventricular Block First Degree (heart block first degree): 3 people, 11.54%
  10. Atrioventricular Block Complete (heart block complete): 3 people, 11.54%

What are the existing conditions these people have? *

  1. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 4 people, 15.38%
  2. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 11.54%
  3. Partial Seizures (seizures which affect only a part of the brain at onset): 3 people, 11.54%
  4. Pain: 3 people, 11.54%
  5. Diabetes: 3 people, 11.54%
  6. Haematoma Infection (infection with collection of blood outside the blood vessels): 1 person, 3.85%
  7. Blood Pressure Abnormal: 1 person, 3.85%
  8. Erysipelas (bacterial skin infection): 1 person, 3.85%
  9. Essential Hypertension (primary hypertension): 1 person, 3.85%
  10. Weight Decreased: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Esidrix and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Esidrix:

Stroke treatments and more:

How severe was Stroke and when was it recovered:

Expand to all the drugs that have ingredients of hydrochlorothiazide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Esidrix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Browse all the conditions that are associated with Stroke:


How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Esidrix) and Esidrix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: