Veletri and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Veletri (epoprostenol sodium) and Profen (ibuprofen). Common drug interactions include nausea among females and staphylococcal infection among males.

The phase IV clinical study analyzes what interactions people have when they take Veletri and Profen. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Veletri?

Veletri has active ingredients of epoprostenol sodium. eHealthMe is studying from 14,196 Veletri users. Check the latest studies of Veletri.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,312 Profen users. Check the latest studies of Profen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

47 people who take Veletri and Profen together, and have interactions are studied.

What are the common drug interactions of Veletri and Profen, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Pain in jaw
Dyspnoea (difficult or laboured respiration)
Hospitalisation
Headache (pain in head)
Epistaxis (bleed from the nose)
Abdominal distension
Fluid retention (an abnormal accumulation of fluid in the blood)
Ascites (accumulation of fluid in the abdominal cavity)

male:

Staphylococcal infection (an infection with staphylococcus bacteria)
Subcutaneous abscess
Dizziness
Fatigue (feeling of tiredness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hepatic failure (liver failure)
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)

What are the common drug interactions of Veletri and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diarrhoea
Pain in jaw
Flushing (the warm, red condition of human skin)
Abdominal distension
Ascites (accumulation of fluid in the abdominal cavity)
Epistaxis (bleed from the nose)
Fluid retention (an abnormal accumulation of fluid in the blood)
Hospitalisation
Nausea (feeling of having an urge to vomit)
Post procedural infection

40-49:

Abdominal pain upper
Fatigue (feeling of tiredness)
Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Aspartate aminotransferase increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Biliary dilatation
Blood albumin decreased

50-59:

Sinusitis (inflammation of sinus)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Headache (pain in head)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Device dislocation
Dyspepsia (indigestion)
Epistaxis (bleed from the nose)
Fluid overload (too much fluid in the blood)
Hypoxia (low oxygen in tissues)
Right ventricular failure (right half of the heart fails to work)

60+:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Fluid retention (an abnormal accumulation of fluid in the blood)
Flushing (the warm, red condition of human skin)
Haematoma (collection of blood outside the blood vessels)
Haemorrhage (bleeding)
Hyperthyroidism (over activity of the thyroid gland)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 39 people, 82.98%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 13 people, 27.66%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

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