Veltassa and Leflunomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Veltassa (patiromer sorbitex calcium) and Leflunomide (leflunomide). Common drug interactions include abdominal pain upper among females and renal impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Veltassa and Leflunomide. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Veltassa?

Veltassa has active ingredients of patiromer sorbitex calcium. eHealthMe is studying from 15,649 Veltassa users. Check the latest studies of Veltassa.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

On Jul, 18, 2026

45 people who take Veltassa and Leflunomide together, and have interactions are studied.

Veltassa and Leflunomide drug interactions.

What are the common drug interactions of Veltassa and Leflunomide, by gender? *:

female:

Abdominal pain upper
Arthralgia (joint pain)
Cardiac failure congestive
Cough
Diarrhoea
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Hepatic steatosis (fatty liver disease)
Hypertension (high blood pressure)
Malaise (a feeling of general discomfort or uneasiness)

male:

Renal impairment (severely reduced kidney function)
Blood creatinine increased
Dehydration (dryness resulting from the removal of water)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Influenza
Death
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Lacunar infarction (a type of stroke)
Renal injury (kidney injury)

What are the common drug interactions of Veltassa and Leflunomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal discomfort
Abdominal pain upper
Arthralgia (joint pain)
Cardiac failure
Cardiac failure congestive
Cough
Diarrhoea
Drug hypersensitivity
Drug ineffective
Drug intolerance (drug sensitivity)

50-59:

Abdominal pain upper
Arthralgia (joint pain)
Cardiac failure congestive
Cough
Diarrhoea
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Hepatic steatosis (fatty liver disease)
Hypertension (high blood pressure)
Malaise (a feeling of general discomfort or uneasiness)

60+:

Death
Blood creatinine increased
Renal impairment (severely reduced kidney function)
Hospitalisation
Hypotension (abnormally low blood pressure)
Fluid overload (too much fluid in the blood)
Pneumonia
Respiratory disorder (respiratory disease)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the existing conditions these people have? *

Abdominal Discomfort: 14 people, 31.11%
Hyperkalemia (damage to or disease of the kidney): 10 people, 22.22%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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