Versed and Soma drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Versed (midazolam hydrochloride) and Soma (carisoprodol). Common drug interactions include weight decreased among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Versed and Soma. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Versed?

Versed has active ingredients of midazolam hydrochloride. It is often used in sedation during medical procedure. eHealthMe is studying from 6,869 Versed users. Check the latest studies of Versed.

What is Soma?

Soma has active ingredients of carisoprodol. It is often used in muscle spasms. eHealthMe is studying from 17,137 Soma users. Check the latest studies of Soma.



On Jul, 20, 2026

50 people who take Versed and Soma together, and have interactions are studied.

Versed and Soma drug interactions.

What are the common drug interactions of Versed and Soma, by gender? *:

female:

  1. Weight decreased
  2. Drug hypersensitivity
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Abdominal pain upper
  5. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  6. Asthenia (weakness)
  7. Chest pain
  8. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  9. Colonic polyp (extra part of colon tissue grow in intestine)
  10. Comminuted fracture (bone has broken into several pieces)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Bone loss
  4. Cellulitis (infection under the skin)
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Confusional state
  7. Deformity (disfigurement)
  8. Dental caries
  9. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  10. Haemorrhagic anaemia (anaemia due to excessive bleeding)

What are the common drug interactions of Versed and Soma, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chronic kidney disease
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Emotional distress
  5. Headache (pain in head)
  6. Photopsia (presence of perceived flashes of light)
  7. Renal failure (kidney dysfunction)
  8. Tinnitus (a ringing in the ears)

40-49:

  1. Chronic kidney disease
  2. Osteonecrosis (death of bone)
  3. Emotional distress
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Anxiety
  6. Asthenia (weakness)
  7. Blood creatinine increased
  8. Bone density decreased
  9. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  10. Colonic polyp (extra part of colon tissue grow in intestine)

50-59:

  1. Drug hypersensitivity
  2. Dysuria (painful or difficult urination)
  3. Fall
  4. Generalised oedema (swelling all over the body)
  5. Loss of consciousness
  6. Migraine (headache)
  7. Muscular weakness (muscle weakness)
  8. Nausea (feeling of having an urge to vomit)
  9. Pain in extremity
  10. Tremor (trembling or shaking movements in one or more parts of your body)

60+:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Muscular weakness (muscle weakness)
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Anxiety
  6. Aortic arteriosclerosis (hardening of the aortic arteries)
  7. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  8. Aortic valve sclerosis (narrowing of the aortic valve)
  9. Apathy
  10. Arthralgia (joint pain)

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 9 people, 18.00%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 14.00%
  3. Metastases To Prostate (cancer spreads to prostate): 7 people, 14.00%
  4. Pain: 7 people, 14.00%
  5. Stress And Anxiety: 5 people, 10.00%
  6. Headache (pain in head): 5 people, 10.00%
  7. Neuropathy Peripheral (surface nerve damage): 4 people, 8.00%
  8. High Blood Pressure: 4 people, 8.00%
  9. Anaesthesia: 4 people, 8.00%
  10. Analgesia: 4 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Versed and Soma?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Versed and Soma:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Versed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Soma:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Versed and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Soma and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on midazolam hydrochloride and carisoprodol (the active ingredients of Versed and Soma, respectively), and Versed and Soma (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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