Vesicare and Caduet drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vesicare (solifenacin succinate) and Caduet (amlodipine besylate; atorvastatin calcium). Common drug interactions include drug ineffective among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Vesicare and Caduet. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Vesicare?
Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,656 Vesicare users. Check the latest studies of Vesicare.
What is Caduet?
Caduet has active ingredients of amlodipine besylate; atorvastatin calcium. It is often used in high blood pressure. eHealthMe is studying from 5,157 Caduet users. Check the latest studies of Caduet.
28 people who take Vesicare and Caduet together, and have interactions are studied.

What are the common drug interactions of Vesicare and Caduet, by gender? *:
female:
- Drug ineffective
- Atrioventricular block (heart block)
- Bradycardia (abnormally slow heart action)
- Chronic kidney disease
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hypoxia (low oxygen in tissues)
- Urinary tract infection
- Febrile neutropenia (fever with reduced white blood cells)
- Hypokalaemia (low potassium)
- Interstitial lung disease
male:
- Drug ineffective
- Pneumonia
- Hypoxia (low oxygen in tissues)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Septic shock (shock due to blood infection)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Constipation
What are the common drug interactions of Vesicare and Caduet, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Dry mouth
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Throat irritation
50-59:
n/a
60+:
- Chronic kidney disease
- Hypoxia (low oxygen in tissues)
- Constipation
- Sleep disorder
- Acute myocardial infarction (acute heart attack)
- Cardiac failure
- Cardiogenic shock (inadequate circulation of blood)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Delirium (wild excitement)
What are the existing conditions these people have? *
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 7 people, 25.00%
- Constipation: 7 people, 25.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 17.86%
- High Blood Cholesterol: 5 people, 17.86%
- Pain: 5 people, 17.86%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 14.29%
- Insomnia (sleeplessness): 4 people, 14.29%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 14.29%
- Type 2 Diabetes: 4 people, 14.29%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 10.71%
* Approximation only. Some reports may have incomplete information.
Do you take Vesicare and Caduet?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Vesicare and Caduet:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vesicare:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Caduet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vesicare and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Caduet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on solifenacin succinate and amlodipine besylate; atorvastatin calcium (the active ingredients of Vesicare and Caduet, respectively), and Vesicare and Caduet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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