Vesicare and Kyprolis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vesicare (solifenacin succinate) and Kyprolis (carfilzomib). Common drug interactions include angioedema among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Vesicare and Kyprolis. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,655 Vesicare users. Check the latest studies of Vesicare.

What is Kyprolis?

Kyprolis has active ingredients of carfilzomib. It is often used in multiple myeloma. eHealthMe is studying from 15,080 Kyprolis users. Check the latest studies of Kyprolis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

17 people who take Vesicare and Kyprolis together, and have interactions are studied.

Vesicare and Kyprolis drug interactions.

What are the common drug interactions of Vesicare and Kyprolis, by gender? *:

female:

Angioedema (rapid swelling of the dermis)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Constipation
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fatigue (feeling of tiredness)
Limb injury
Localised infection (infection at the single location)
Oedema (fluid collection in tissue)
Renal disorder (kidney disease)
Throat irritation

male:

Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Ejection fraction decreased (systolic heart failure)
Headache (pain in head)
Left ventricular dysfunction
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Listless (lack of interest, energy, or spirit)
Mitral valve calcification (calcium deposit in mitral valve)
Mitral valve incompetence (inefficient heart valve)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Vesicare and Kyprolis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Platelet count decreased

60+:

Angioedema (rapid swelling of the dermis)
Fatigue (feeling of tiredness)
Asthenia (weakness)
Back pain
Blood cholesterol increased
Chronic kidney disease
Confusional state
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug intolerance (drug sensitivity)

What are the existing conditions these people have? *

Fungal Infection: 1 person, 5.88%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 5.88%
Fever: 1 person, 5.88%
Cough: 1 person, 5.88%
Bacterial Infection: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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