Vesicare and Lysine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vesicare (solifenacin succinate) and Lysine (lysine). Common drug interactions include hypoaesthesia among females and aortic aneurysm among males.

The phase IV clinical study analyzes what interactions people have when they take Vesicare and Lysine. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Vesicare?

Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,655 Vesicare users. Check the latest studies of Vesicare.

What is Lysine?

Lysine has active ingredients of lysine. It is often used in herpes labialis (oral herpes simplex). eHealthMe is studying from 16,525 Lysine users. Check the latest studies of Lysine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

39 people who take Vesicare and Lysine together, and have interactions are studied.

What are the common drug interactions of Vesicare and Lysine, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Impaired gastric emptying
Joint swelling
Loss of consciousness
Mobility decreased (ability to move is reduced)
Muscular weakness (muscle weakness)
Neuralgia (pain in one or more nerves)
Nuclear magnetic resonance imaging brain
Optic nerve disorder (disease of optic nerve)

male:

Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Behcet's syndrome (involves inflammation of the blood vessels)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Tobacco abuse
Activated partial thromboplastin time prolonged
Acute respiratory distress syndrome
Dyspnoea (difficult or laboured respiration)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hallucination, visual (seeing things that aren't there)
Hypovolaemia (a decreased volume of circulating blood in the body)

What are the common drug interactions of Vesicare and Lysine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Insomnia (sleeplessness)
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Restlessness (not able to rest)

30-39:

Injection site haemorrhage (bleeding from injection site)

40-49:

Insomnia (sleeplessness)
Anxiety
Aphasia (damage to the parts of the brain that control language)
Asthenia (weakness)
Asthma
Cataplexy (loss of muscle tone accompanied by full conscious awareness)
Dizziness
Dyspnoea (difficult or laboured respiration)
Enuresis (repeated inability to control urination)
Fall

50-59:

Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Behcet's syndrome (involves inflammation of the blood vessels)
Blood pressure decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colitis (inflammation of colon)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Intestinal polyp (small growths in the bowel with the potential for further growth)
Pulmonary mass
Renal cyst (kidney cyst)
Renal disorder (kidney disease)

60+:

Abdominal pain upper
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Abdominal pain
Activated partial thromboplastin time prolonged
Acute respiratory distress syndrome
Cystitis (inflammation of the wall of the bladder)
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Dry eye (lack of adequate tears)
Dyspnoea (difficult or laboured respiration)
Encephalopathy (functioning of the brain is affected by some agent or condition)

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 8 people, 20.51%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 20.51%
High Blood Cholesterol: 6 people, 15.38%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 15.38%
Incontinence (lack of moderation or self-control): 5 people, 12.82%
Bone Disorder: 4 people, 10.26%
Respiratory Disorder (respiratory disease): 4 people, 10.26%
Fibrinous Bronchitis (inflammation of the bronchial mucous membrane, accompanied by a fibrinous exudation): 4 people, 10.26%
Nausea (feeling of having an urge to vomit): 3 people, 7.69%
Weight Loss: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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