Vesicare and Sinequan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vesicare (solifenacin succinate) and Sinequan (doxepin hydrochloride). Common drug interactions include pneumonia among females.
The phase IV clinical study analyzes what interactions people have when they take Vesicare and Sinequan. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Vesicare?
Vesicare has active ingredients of solifenacin succinate. It is often used in urge incontinence. eHealthMe is studying from 30,656 Vesicare users. Check the latest studies of Vesicare.
What is Sinequan?
Sinequan has active ingredients of doxepin hydrochloride. It is often used in depression. eHealthMe is studying from 1,879 Sinequan users. Check the latest studies of Sinequan.
12 people who take Vesicare and Sinequan together, and have interactions are studied.

What are the common drug interactions of Vesicare and Sinequan, by gender? *:
female:
- Pneumonia
- Cystitis (inflammation of the wall of the bladder)
- Dyspnoea (difficult or laboured respiration)
- Foot fracture
- Gait disturbance
- Gastric ulcer haemorrhage (bleeding ulcer of stomach)
- Headache (pain in head)
- Hypotension (abnormally low blood pressure)
- Lung disorder (lung disease)
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
male:
n/a
What are the common drug interactions of Vesicare and Sinequan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Abdominal pain
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
- Carotid artery stenosis (narrowing of carotid artery)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Dyspnoea (difficult or laboured respiration)
- Foot fracture
- Gastric ulcer haemorrhage (bleeding ulcer of stomach)
- Headache (pain in head)
- Lung disorder (lung disease)
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
60+:
- Cystitis (inflammation of the wall of the bladder)
- Fall
- Disease progression
- Intervertebral disc protrusion (spinal disc protrusion)
- Metastases to bone (cancer spreads to bone)
- Metastases to liver (cancer spreads to liver)
- Neoplasm progression (growth of tumour)
- Pain in extremity
- Renal failure (kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
What are the existing conditions these people have? *
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 41.67%
- Pain: 3 people, 25.00%
- High Blood Cholesterol: 3 people, 25.00%
- High Blood Pressure: 3 people, 25.00%
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 16.67%
- Blood Pressure Abnormal: 2 people, 16.67%
- Cardiac Disorder: 2 people, 16.67%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 16.67%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 16.67%
- Dyspnea (difficult or laboured breathing): 2 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Vesicare and Sinequan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Vesicare and Sinequan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vesicare:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sinequan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vesicare and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sinequan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on solifenacin succinate and doxepin hydrochloride (the active ingredients of Vesicare and Sinequan, respectively), and Vesicare and Sinequan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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