Vfend and Cefazolin sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vfend (voriconazole) and Cefazolin sodium (cefazolin sodium). Common drug interactions include pain in extremity among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Vfend and Cefazolin sodium. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Vfend?

Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.

What is Cefazolin sodium?

Cefazolin sodium has active ingredients of cefazolin sodium. eHealthMe is studying from 3,649 Cefazolin sodium users. Check the latest studies of Cefazolin sodium.

On Jul, 26, 2026

23 people who take Vfend and Cefazolin sodium together, and have interactions are studied.

Vfend and Cefazolin sodium drug interactions.

What are the common drug interactions of Vfend and Cefazolin Sodium, by gender? *:

female:

Pain in extremity
Thrombocytopenia (decrease of platelets in blood)
Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
Epistaxis (bleed from the nose)
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gingival bleeding (bleeding gums)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia fungal
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

male:

Pneumonia
Herpes zoster
Drug level decreased
Gamma-glutamyltransferase increased
Ileus (a painful obstruction of the ileum or other part of the intestine)
Malaise (a feeling of general discomfort or uneasiness)
Photophobia (extreme sensitivity to light)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Visual impairment
Disseminated intravascular coagulation (systemic activation of blood coagulation)

What are the common drug interactions of Vfend and Cefazolin Sodium, by age (0-1 to 60+)? *:

0-1:

Peptic ulcer haemorrhage (peptic ulcer bleeding)
Pulmonary oedema (fluid accumulation in the lungs)
Renal impairment (severely reduced kidney function)
Venoocclusive liver disease (small veins in the liver are obstructed)

2-9:

Adenovirus infection
Angiopathy (generic term for a disease of the blood vessels)
Ascites (accumulation of fluid in the abdominal cavity)
Coagulopathy (blood's ability to clot is impaired)
Cytokine storm (over-protective immune response that can actually be fatal)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Pulmonary haemorrhage (acute bleeding from the lung)
Pyrexia (fever)
Renal impairment (severely reduced kidney function)
Respiratory disorder (respiratory disease)

10-19:

Febrile neutropenia (fever with reduced white blood cells)
Pain in extremity
Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
Epistaxis (bleed from the nose)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gingival bleeding (bleeding gums)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia fungal
Blood creatinine increased
Disseminated intravascular coagulation (systemic activation of blood coagulation)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Altered state of consciousness (altered state of mind)
Aspergillosis oral
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Herpes zoster
Ileus (a painful obstruction of the ileum or other part of the intestine)
Platelet count decreased
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
Hallucination, visual (seeing things that aren't there)
Infection

60+:

Interstitial lung disease
Pneumonia
Thrombocytopenia (decrease of platelets in blood)
Visual impairment
Platelet count decreased
Renal disorder (kidney disease)
Agitation (state of anxiety or nervous excitement)
Delirium (wild excitement)
Dyskinesia (abnormality or impairment of voluntary movement)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

What are the existing conditions these people have? *

Stomatitis (inflammation of mucous membrane of mouth): 6 people, 26.09%
Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 26.09%
Adult T-Cell Lymphoma/leukaemia (cancer of the immune system's own t-cells): 6 people, 26.09%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 6 people, 26.09%
Constipation: 6 people, 26.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 26.09%
Hepatitis B: 6 people, 26.09%
Pain: 6 people, 26.09%
Pneumonia: 6 people, 26.09%
Proctitis (inflammation of the rectum and anus): 6 people, 26.09%

* Approximation only. Some reports may have incomplete information.

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