Vfend and Lexapro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vfend (voriconazole) and Lexapro (escitalopram oxalate). Common drug interactions include thirst among females and bacterial infection among males.
The phase IV clinical study analyzes what interactions people have when they take Vfend and Lexapro. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Vfend?
Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.
What is Lexapro?
Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,465 Lexapro users. Check the latest studies of Lexapro.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
41 people who take Vfend and Lexapro together, and have interactions are studied.

What are the common drug interactions of Vfend and Lexapro, by gender? *:
female:
- Thirst
- Trichorrhexis (a condition in which the hairs break)
- Visual impairment
- Death
- Headache (pain in head)
- Infection
- Influenza like illness
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Night sweats (sweating in night)
- Pain in extremity
male:
- Bacterial infection
- Hallucination (an experience involving the perception of something not present)
- Cytomegalovirus gastritis (virus infection of stomach)
- Dementia (madness)
- Limb discomfort (discomfort in leg)
- Myeloid leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts)
- Neoplasm recurrence (reoccurrence of tumour)
- Nephrolithiasis (calculi in the kidneys)
- Pneumonia fungal
- Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)
What are the common drug interactions of Vfend and Lexapro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Bradycardia (abnormally slow heart action)
- Fatigue (feeling of tiredness)
- Haemoglobin decreased
- Hypotension (abnormally low blood pressure)
- Myalgia (muscle pain)
- Pyrexia (fever)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Stomatitis (inflammation of mucous membrane of mouth)
- Streptococcal bacteraemia (a bacterial infection of blood)
- Syncope (loss of consciousness with an inability to maintain postural tone)
20-29:
n/a
30-39:
- Atelectasis (partial or complete collapse of the lung)
- Blood albumin decreased
- Blood alkaline phosphatase increased
- Blood calcium decreased
- Blood chloride decreased
- Blood creatinine decreased
- Blood glucose increased
- Blood lactate dehydrogenase increased
- Blood magnesium decreased
- Blood sodium decreased
40-49:
- Alopecia (absence of hair from areas of the body)
- Hypomenorrhoea (a diminution of the menstrual flow or a shortening of the duration of menstruation)
- Social problem
- Diarrhoea
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Vomiting
50-59:
- Blood alkaline phosphatase increased
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
- Renal failure (kidney dysfunction)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
- Unresponsive to stimuli
60+:
- Fatigue (feeling of tiredness)
- Pyrexia (fever)
- Hypertrichosis (hair growth on the body in an amount considered abnormal)
- Photosensitivity reaction
- Skin discolouration (change of skin colour)
- Vision blurred
- Dyspnoea (difficult or laboured respiration)
- Anaemia (lack of blood)
- Cholecystitis (infection of gallbladder)
- Cytomegalovirus gastritis (virus infection of stomach)
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 5 people, 12.20%
- Pain: 4 people, 9.76%
- Nausea And Vomiting: 4 people, 9.76%
- Indigestion: 4 people, 9.76%
- Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 4 people, 9.76%
- Gastric Ulcer (stomach ulcer): 4 people, 9.76%
- Fungal Infection: 4 people, 9.76%
- Hypersensitivity: 3 people, 7.32%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 7.32%
* Approximation only. Some reports may have incomplete information.
Do you take Vfend and Lexapro?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Vfend and Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vfend:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vfend and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lexapro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on voriconazole and escitalopram oxalate (the active ingredients of Vfend and Lexapro, respectively), and Vfend and Lexapro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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