Viagra and Zemplar drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Viagra (sildenafil citrate) and Zemplar (paricalcitol). Common drug interactions include drug ineffective among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Viagra and Zemplar. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.
What is Viagra?
Viagra has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 63,865 Viagra users. Check the latest studies of Viagra.
What is Zemplar?
Zemplar has active ingredients of paricalcitol. It is often used in kidney disease. eHealthMe is studying from 15,494 Zemplar users. Check the latest studies of Zemplar.
51 people who take Viagra and Zemplar together, and have interactions are studied.

What are the common drug interactions of Viagra and Zemplar, by gender? *:
female:
- Drug ineffective
- Haematuria (presence of blood in urine)
- Leukocyturia (presence of white blood cells in urine)
- Transitional cell carcinoma (cancer tumour inner most layer of urinary system)
- Urinary tract infection enterococcal
male:
- Arthralgia (joint pain)
- Erythema multiforme (a type of hypersensitivity reaction)
- Anxiety
- Mitral valve incompetence (inefficient heart valve)
- Pain
- Skin disorder (skin disease)
- Back pain
- Haemorrhage (bleeding)
- Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
- Diarrhoea
What are the common drug interactions of Viagra and Zemplar, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
40-49:
- Pericarditis uraemic
- Pleural effusion (water on the lungs)
- Rosacea (a skin condition that causes facial redness)
- Sinusitis (inflammation of sinus)
- Skin disorder (skin disease)
- Swelling
- Vascular calcification (deposits of calcium in the blood vessels)
- Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
- Asthenia (weakness)
- Back pain
50-59:
- Restless legs syndrome (a powerful urge to move your legs)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arthralgia (joint pain)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Back pain
- Balance disorder
- Emotional distress
- Fatigue (feeling of tiredness)
- Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
60+:
- Cerebellar haemorrhage (bleeding in cerebeller)
- Hemiplegia (paralysis of one side of the body)
- Abnormal behaviour
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood creatinine increased
- Blood phosphorus increased
- Chronic kidney disease
- Diastolic dysfunction
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Dyspnoea (difficult or laboured respiration)
What are the existing conditions these people have? *
- High Blood Cholesterol: 12 people, 23.53%
- Pain: 10 people, 19.61%
- High Blood Pressure: 9 people, 17.65%
- Blood Phosphorus Increased: 6 people, 11.76%
- Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 6 people, 11.76%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.80%
- Nuclear Magnetic Resonance Imaging Abdominal: 5 people, 9.80%
- Cardiac Disorder: 4 people, 7.84%
- Indigestion: 4 people, 7.84%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Viagra and Zemplar?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Viagra and Zemplar:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Viagra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zemplar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Viagra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zemplar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on sildenafil citrate and paricalcitol (the active ingredients of Viagra and Zemplar, respectively), and Viagra and Zemplar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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