Viberzi and Bentyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viberzi (eluxadoline) and Bentyl (dicyclomine hydrochloride). Common drug interactions include pancreatitis among females and cardiomyopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Viberzi and Bentyl. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Viberzi?

Viberzi has active ingredients of eluxadoline. eHealthMe is studying from 3,077 Viberzi users. Check the latest studies of Viberzi.

What is Bentyl?

Bentyl has active ingredients of dicyclomine hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 10,754 Bentyl users. Check the latest studies of Bentyl.



On Jul, 19, 2026

37 people who take Viberzi and Bentyl together, and have interactions are studied.

Viberzi and Bentyl drug interactions.

What are the common drug interactions of Viberzi and Bentyl, by gender? *:

female:

  1. Pancreatitis (inflammation of pancreas)
  2. Constipation
  3. Nausea (feeling of having an urge to vomit)
  4. Pain
  5. Sedation
  6. Back pain
  7. Chronic kidney disease
  8. Fall
  9. Head discomfort
  10. Limb discomfort (discomfort in leg)

male:

  1. Cardiomyopathy (weakening of the heart muscle)
  2. Constipation
  3. Rash
  4. Suicidal ideation
  5. Therapeutic response unexpected
  6. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  7. Drug ineffective
  8. Dyschezia (difficulty in defecating)
  9. Feeling hot
  10. Flushing (the warm, red condition of human skin)

What are the common drug interactions of Viberzi and Bentyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Pancreatitis (inflammation of pancreas)

20-29:

  1. Suicidal ideation

30-39:

  1. Nausea (feeling of having an urge to vomit)
  2. Feeling hot
  3. Flushing (the warm, red condition of human skin)
  4. Gastric disorder (disease of stomach)
  5. Hyperhidrosis (abnormally increased sweating)
  6. Neuralgia (pain in one or more nerves)
  7. Pancreatitis (inflammation of pancreas)

40-49:

  1. Back injury
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Cardiomyopathy (weakening of the heart muscle)
  4. Lower respiratory tract infection
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Pancreatitis acute (sudden inflammation of pancreas)
  7. Pancreatitis chronic (chronic inflammation of pancreas)
  8. Sinusitis (inflammation of sinus)

50-59:

  1. Back pain
  2. Nausea (feeling of having an urge to vomit)
  3. Pancreatitis (inflammation of pancreas)
  4. Abdominal pain upper
  5. Constipation
  6. Cough
  7. Fall
  8. Hospitalisation
  9. Hyperhidrosis (abnormally increased sweating)
  10. Malaise (a feeling of general discomfort or uneasiness)

60+:

  1. Chronic kidney disease
  2. Constipation
  3. Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
  4. Pancreatitis (inflammation of pancreas)
  5. Psoriasis (immune-mediated disease that affects the skin)
  6. Rash
  7. Amylase increased
  8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  9. Dizziness
  10. Dyschezia (difficulty in defecating)

What are the existing conditions these people have? *

  1. Indigestion: 5 people, 13.51%
  2. Diarrhea: 5 people, 13.51%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 10.81%
  4. Stress And Anxiety: 3 people, 8.11%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 8.11%
  6. Muscle Spasms (muscle contraction): 3 people, 8.11%
  7. High Blood Pressure: 3 people, 8.11%
  8. High Blood Cholesterol: 3 people, 8.11%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.11%
  10. Vitamin D Decreased: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Viberzi and Bentyl?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Viberzi and Bentyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Viberzi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bentyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viberzi and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bentyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on eluxadoline and dicyclomine hydrochloride (the active ingredients of Viberzi and Bentyl, respectively), and Viberzi and Bentyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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