Viberzi and Nexium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viberzi (eluxadoline) and Nexium (esomeprazole magnesium). Common drug interactions include chronic kidney disease among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Viberzi and Nexium. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Viberzi?

Viberzi has active ingredients of eluxadoline. eHealthMe is studying from 3,077 Viberzi users. Check the latest studies of Viberzi.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.

On Jul, 29, 2026

69 people who take Viberzi and Nexium together, and have interactions are studied.

What are the common drug interactions of Viberzi and Nexium, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anxiety
Nephrogenic anaemia (anaemia due to kidney disease)
Renal tubular necrosis (death of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Abdominal pain
Headache (pain in head)

male:

Drug ineffective
Abdominal pain
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Pain
Constipation
Enzyme level increased
Sphincter of oddi dysfunction (dysfunction of a muscular valve that controls the flow of digestive juices)
Anaemia (lack of blood)

What are the common drug interactions of Viberzi and Nexium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Vomiting

30-39:

Enzyme level increased
Sphincter of oddi dysfunction (dysfunction of a muscular valve that controls the flow of digestive juices)
Abdominal pain
Drug ineffective
Pruritus (severe itching of the skin)
Swelling
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

Sinusitis (inflammation of sinus)
Stoma site reaction (reaction at abdominal opening)
Surgical failure
Upper respiratory tract infection
Adenoma benign (non-cancerous tumour -secreting)
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Colitis ulcerative (inflammation of colon with ulcer)
Cough
Dizziness

50-59:

Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Anxiety
Asthenia (weakness)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Dizziness
Dry mouth
Epigastric discomfort
Eye swelling

60+:

Nausea (feeling of having an urge to vomit)
Abdominal pain
Pancreatitis (inflammation of pancreas)
Abdominal pain upper
Abdominal distension
Anxiety
Change of bowel habit
Chest pain
Diarrhoea
Drug ineffective

What are the existing conditions these people have? *

Irritable Bowel Syndrome: 33 people, 47.83%
Depression: 13 people, 18.84%
High Blood Pressure: 9 people, 13.04%
Diarrhea: 9 people, 13.04%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 11.59%
Stress And Anxiety: 7 people, 10.14%
Pain: 7 people, 10.14%
Immunodeficiency Common Variable: 7 people, 10.14%
High Blood Cholesterol: 6 people, 8.70%
Sleep Disorder: 5 people, 7.25%

* Approximation only. Some reports may have incomplete information.

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