Vibramycin and Glucophage drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vibramycin (doxycycline) and Glucophage (metformin hydrochloride). Common drug interactions include dyspnoea among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Vibramycin and Glucophage. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Vibramycin?

Vibramycin has active ingredients of doxycycline. It is often used in acne. eHealthMe is studying from 1,692 Vibramycin users. Check the latest studies of Vibramycin.

What is Glucophage?

Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.

On Jul, 02, 2026

25 people who take Vibramycin and Glucophage together, and have interactions are studied.

Vibramycin and Glucophage drug interactions.

What are the common drug interactions of Vibramycin and Glucophage, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Osteomyelitis (infection of bone)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Diabetic foot infection
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Graft complication
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Weight decreased
Abdominal pain lower
Dermatitis allergic (inflammation of the skin due allergic reaction)

male:

Cellulitis (infection under the skin)
Dyspnoea (difficult or laboured respiration)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
International normalised ratio increased
Pyrexia (fever)
Asthenia (weakness)
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)
Drug level increased

What are the common drug interactions of Vibramycin and Glucophage, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Osteomyelitis (infection of bone)
Diabetic foot infection
Graft complication
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)

40-49:

Fall
Wrist fracture

50-59:

Cellulitis (infection under the skin)
Electrocardiogram qt prolonged
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Heart rate irregular
Muscular weakness (muscle weakness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain in extremity
Pancreatitis (inflammation of pancreas)
Pyrexia (fever)

60+:

Dyspnoea (difficult or laboured respiration)
Abdominal distension
Coagulopathy (blood's ability to clot is impaired)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
International normalised ratio increased
Weight decreased
Asthenia (weakness)
Contusion (a type of hematoma of tissue in which capillaries)
Cough

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 40.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 36.00%
Cellulitis (infection under the skin): 7 people, 28.00%
Type 2 Diabetes: 7 people, 28.00%
Neuropathy Peripheral (surface nerve damage): 6 people, 24.00%
Sinusitis (inflammation of sinus): 6 people, 24.00%
Rosacea (a skin condition that causes facial redness): 6 people, 24.00%
Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 24.00%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 6 people, 24.00%
Ocular Rosacea (redness, irritation or burning of the eyes): 6 people, 24.00%

* Approximation only. Some reports may have incomplete information.

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