Vicodin es and Ranitidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin es (acetaminophen; hydrocodone bitartrate) and Ranitidine (ranitidine). Common drug interactions include activities of daily living impaired among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Vicodin es and Ranitidine. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin es?

Vicodin es has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 2,450 Vicodin es users. Check the latest studies of Vicodin es.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

36 people who take Vicodin es and Ranitidine together, and have interactions are studied.

Vicodin es and Ranitidine drug interactions.

What are the common drug interactions of Vicodin Es and Ranitidine, by gender? *:

female:

Activities of daily living impaired
Alopecia (absence of hair from areas of the body)
Anxiety
Asthenia (weakness)
Back injury
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
C-reactive protein increased
Cardiac arrest
Cholecystitis acute (rapid infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

male:

Anaemia (lack of blood)
Arthralgia (joint pain)
Insomnia (sleeplessness)
Oedema peripheral (superficial swelling)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Urine flow decreased

What are the common drug interactions of Vicodin Es and Ranitidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal distension
Anxiety
Cholecystitis acute (rapid infection of gallbladder)
Constipation
Depression
Diarrhoea
Gallbladder disorder
Hepatic enzyme increased
Injury
Scar

10-19:

n/a

20-29:

n/a

30-39:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Gallbladder injury
Hypersensitivity
Infusion related reaction
Injury
Insomnia (sleeplessness)
Pruritus (severe itching of the skin)
Restless legs syndrome (a powerful urge to move your legs)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

Blood pressure increased
Depression
Dyspnoea (difficult or laboured respiration)
Suicidal ideation
Surgery

50-59:

Arthralgia (joint pain)
Hot flush (sudden feelings of heat)
Injection site erythema (redness at injection site)
Injection site reaction
Nausea (feeling of having an urge to vomit)
Urticaria (rash of round, red welts on the skin that itch intensely)
Abdominal discomfort
Asthenia (weakness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic kidney disease

60+:

Insomnia (sleeplessness)
Anaemia (lack of blood)
Hypoaesthesia (reduced sense of touch or sensation)
Oedema peripheral (superficial swelling)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Urine flow decreased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 22.22%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 19.44%
Immunodeficiency Common Variable: 5 people, 13.89%
Sleep Disorder: 3 people, 8.33%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 8.33%
Depression: 3 people, 8.33%
Diabetes: 3 people, 8.33%
High Blood Cholesterol: 3 people, 8.33%
Muscle Spasms (muscle contraction): 3 people, 8.33%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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