Vicodin hp and Morphine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin hp (acetaminophen; hydrocodone bitartrate) and Morphine (morphine sulfate). Common drug interactions include arthralgia among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Vicodin hp and Morphine. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin hp?

Vicodin hp has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 534 Vicodin hp users. Check the latest studies of Vicodin hp.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.

On Jul, 18, 2026

30 people who take Vicodin hp and Morphine together, and have interactions are studied.

Vicodin hp and Morphine drug interactions.

What are the common drug interactions of Vicodin Hp and Morphine, by gender? *:

female:

Arthralgia (joint pain)
Asthma
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Facial palsy (paralysis of face nerve)
Hepatic enzyme increased
Herpes zoster
Immune system disorder
Jaw disorder (jaw disease)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

male:

Death
Fatigue (feeling of tiredness)
Blood immunoglobulin e increased
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Conjunctivitis (pink eye)
Decreased appetite
Depressed level of consciousness
Depression

What are the common drug interactions of Vicodin Hp and Morphine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Headache (pain in head)
Toothache (tooth pain)

40-49:

Night sweats (sweating in night)
Otitis externa (external ear infection)
Pallor
Paralysis
Pitting oedema (skin discoloration)
Pleuritic pain
Pneumonia
Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)
Poor quality sleep
Post herpetic neuralgia (neuralgia caused by the varicella zoster virus)

50-59:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Infection
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Overdose
White blood cell count increased
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Vomiting
Abnormal behaviour

60+:

Nausea (feeling of having an urge to vomit)
Blood pressure increased
Death
Dizziness
Drug ineffective
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Hip fracture
Hyperglycaemic hyperosmolar nonketotic syndrome (too much sugar (glucose) in your blood)
Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
Staphylococcal bacteraemia (a bacterial infection of blood)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 16.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 16.67%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 3 people, 10.00%
Back Pain: 3 people, 10.00%
Asthma: 3 people, 10.00%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 2 people, 6.67%
Pneumonia Pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa): 2 people, 6.67%
Osteoporosis (bones weak and more likely to break): 2 people, 6.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.67%
Multiple Myeloma (cancer of the plasma cells): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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