Vicodin and Lamisil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin (acetaminophen; hydrocodone bitartrate) and Lamisil (terbinafine hydrochloride). Common drug interactions include peptic ulcer among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Vicodin and Lamisil. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

On Jul, 27, 2026

71 people who take Vicodin and Lamisil together, and have interactions are studied.

What are the common drug interactions of Vicodin and Lamisil, by gender? *:

female:

Peptic ulcer
Weight decreased
Anaemia postoperative
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Hypersensitivity
Hypoaesthesia (reduced sense of touch or sensation)

male:

Anxiety
Depression
Arthralgia (joint pain)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pneumonia
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Ear pain
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)

What are the common drug interactions of Vicodin and Lamisil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Adverse event
Colitis ulcerative (inflammation of colon with ulcer)
Diabetes mellitus inadequate control
Emotional distress
Erectile dysfunction
Headache (pain in head)
Maternal exposure during pregnancy (use of substance during pregnancy)
Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum)
Therapeutic response delayed (late preventive response)

40-49:

Anxiety
Depression
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Breast cancer
Chest pain
Decreased interest
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Ear pain
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

50-59:

Constipation
Emotional distress
Hypersensitivity
Pneumonia
Anaemia postoperative
Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Lumbar radiculopathy (radicular pain in the low back and legs)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

Anxiety
Asthenia (weakness)
Weight decreased
Activities of daily living impaired
Anaemia (lack of blood)
Arthropathy
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 9.86%
Diabetes: 7 people, 9.86%
Sleep Disorder: 6 people, 8.45%
Hypersensitivity: 6 people, 8.45%
Depression: 6 people, 8.45%
Type 2 Diabetes: 5 people, 7.04%
High Blood Pressure: 5 people, 7.04%
High Blood Cholesterol: 5 people, 7.04%
Swelling: 4 people, 5.63%
Neuropathy Peripheral (surface nerve damage): 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

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