Carvedilol and Mysoline drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Carvedilol (carvedilol) and Mysoline (primidone). Common drug interactions include small intestinal obstruction among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Carvedilol and Mysoline. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.
What is Carvedilol?
Carvedilol has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 112,649 Carvedilol users. Check the latest studies of Carvedilol.
What is Mysoline?
Mysoline has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 2,849 Mysoline users. Check the latest studies of Mysoline.
40 people who take Carvedilol and Mysoline together, and have interactions are studied.

What are the common drug interactions of Carvedilol and Mysoline, by gender? *:
female:
- Small intestinal obstruction (blockage in small intestine)
- Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
- Confusional state
- Encephalomalacia (localized softening of the brain substance, due to haemorrhage or inflammation)
- Neuropathy peripheral (surface nerve damage)
- Cystitis (inflammation of the wall of the bladder)
- Herpes simplex (herpes simplex is a common viral infection)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Ataxia (loss of full control of bodily movements)
- Balance disorder
male:
- Renal failure (kidney dysfunction)
- Dyspnoea (difficult or laboured respiration)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hypertensive nephropathy (hypertensive renal disease)
- Malaise (a feeling of general discomfort or uneasiness)
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Renal failure chronic (long lasting kidney dysfunction)
- Restless legs syndrome (a powerful urge to move your legs)
- Rosacea (a skin condition that causes facial redness)
What are the common drug interactions of Carvedilol and Mysoline, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Chronic kidney disease
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
40-49:
n/a
50-59:
- Cystitis (inflammation of the wall of the bladder)
- Herpes simplex (herpes simplex is a common viral infection)
- Small intestinal obstruction (blockage in small intestine)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Ataxia (loss of full control of bodily movements)
- Balance disorder
- Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
- Cerebral atrophy (decrement in size of brain)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Cerebral small vessel ischaemic disease (inadequate blood supply to small blood vessel of brain)
60+:
- Renal failure (kidney dysfunction)
- Dyspnoea (difficult or laboured respiration)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hypertensive nephropathy (hypertensive renal disease)
- Malaise (a feeling of general discomfort or uneasiness)
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Renal failure chronic (long lasting kidney dysfunction)
- Restless legs syndrome (a powerful urge to move your legs)
- Rosacea (a skin condition that causes facial redness)
What are the existing conditions these people have? *
- Pain: 11 people, 27.50%
- Nausea (feeling of having an urge to vomit): 11 people, 27.50%
- Diabetes: 11 people, 27.50%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 25.00%
- High Blood Cholesterol: 9 people, 22.50%
- Fever: 8 people, 20.00%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 17.50%
- Stress And Anxiety: 7 people, 17.50%
- Headache (pain in head): 7 people, 17.50%
- Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 7 people, 17.50%
* Approximation only. Some reports may have incomplete information.
Do you take Carvedilol and Mysoline?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Carvedilol (112,649 reports)
- Mysoline (2,849 reports)
Browse all drug interactions of Carvedilol and Mysoline:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Carvedilol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Mysoline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Carvedilol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mysoline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carvedilol and primidone (the active ingredients of Carvedilol and Mysoline, respectively), and Carvedilol and Mysoline (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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