Aleve and Soliris drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Aleve (naproxen sodium) and Soliris (eculizumab). Common drug interactions include haemoglobin decreased among females.
The phase IV clinical study analyzes what interactions people have when they take Aleve and Soliris. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Aleve?
Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.
What is Soliris?
Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.
25 people who take Aleve and Soliris together, and have interactions are studied.

What are the common drug interactions of Aleve and Soliris, by gender? *:
female:
- Haemoglobin decreased
- Fatigue (feeling of tiredness)
- Pallor
- Blood urine present
- Anxiety
- Arthralgia (joint pain)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cataract (clouding of the lens inside the eye)
- Constipation
- Contusion (a type of hematoma of tissue in which capillaries)
male:
n/a
What are the common drug interactions of Aleve and Soliris, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Haemoglobin decreased
- Fatigue (feeling of tiredness)
- Nasopharyngitis (inflammation of the nasopharynx)
- Cystitis (inflammation of the wall of the bladder)
- Blood iron increased
- Migraine (headache)
- Ocular icterus (presence of jaundice seen in the sclera of the eye)
- Pallor
- Back pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
30-39:
- Blood urine present
- Fatigue (feeling of tiredness)
- Haemoglobin decreased
- Infection
- Myalgia (muscle pain)
- Red blood cell count decreased
- Reticulocyte count increased
- White blood cell count decreased
- White blood cell count increased
40-49:
- Abdominal distension
- Dermatitis herpetiformis (chronic blistering skin condition, characterized by blisters filled with a watery fluid)
- Rash papular (redness with papule)
- Rash pruritic (redness with itching)
- Sinus headache (headache caused by sinus infections)
- Skin ulcer
50-59:
- Agitation (state of anxiety or nervous excitement)
- Contusion (a type of hematoma of tissue in which capillaries)
- Pruritus (severe itching of the skin)
60+:
- Anxiety
- Arthralgia (joint pain)
- Fatigue (feeling of tiredness)
- Incontinence (lack of moderation or self-control)
- Nausea (feeling of having an urge to vomit)
- Oedema (fluid collection in tissue)
- Pain in extremity
- Poor venous access
- Rash
- Upper-airway cough syndrome
What are the existing conditions these people have? *
- Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 20 people, 80.00%
- Headache (pain in head): 14 people, 56.00%
- Birth Control: 8 people, 32.00%
- Nasopharyngitis (inflammation of the nasopharynx): 5 people, 20.00%
- Dry Throat: 5 people, 20.00%
- Nausea (feeling of having an urge to vomit): 3 people, 12.00%
- Hypersensitivity: 3 people, 12.00%
- Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 8.00%
- Sleep Disorder: 2 people, 8.00%
- Itching: 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Aleve and Soliris?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Aleve and Soliris:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Aleve:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Soliris:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aleve and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Soliris and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on naproxen sodium and eculizumab (the active ingredients of Aleve and Soliris, respectively), and Aleve and Soliris (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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