Vicodin and Mefoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vicodin (acetaminophen; hydrocodone bitartrate) and Mefoxin (cefoxitin sodium). Common drug interactions include asthma among females.

The phase IV clinical study analyzes what interactions people have when they take Vicodin and Mefoxin. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

What is Mefoxin?

Mefoxin has active ingredients of cefoxitin sodium. eHealthMe is studying from 280 Mefoxin users. Check the latest studies of Mefoxin.



On Jul, 08, 2026

38 people who take Vicodin and Mefoxin together, and have interactions are studied.

Vicodin and Mefoxin drug interactions.

What are the common drug interactions of Vicodin and Mefoxin, by gender? *:

female:

  1. Asthma
  2. Joint dislocation (a joint position is changed from normal position)
  3. Cellulitis (infection under the skin)
  4. Colitis ulcerative (inflammation of colon with ulcer)
  5. Dental caries
  6. Diarrhoea
  7. Enteritis (inflammation of the small intestine)
  8. Enterococcal infection
  9. Escherichia infection (bacterial infection by escherichia coli)
  10. Essential thrombocythaemia (chronic blood cancer)

male:

n/a

What are the common drug interactions of Vicodin and Mefoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cholecystitis chronic (long lasting infection of gallbladder)
  2. Injury
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Gallbladder disorder
  5. Gastritis (inflammation of stomach)
  6. Pancreatitis (inflammation of pancreas)
  7. Pulmonary embolism (blockage of the main artery of the lung)

30-39:

  1. Cholecystitis chronic (long lasting infection of gallbladder)
  2. Pulmonary embolism (blockage of the main artery of the lung)

40-49:

  1. Abdominal distension
  2. Abdominal pain upper
  3. Cholecystitis (infection of gallbladder)
  4. Dyspepsia (indigestion)
  5. Injury

50-59:

  1. Appendicitis (inflammation of the appendix)
  2. Aptyalism (deficiency or absence of saliva)
  3. Dental caries
  4. Diarrhoea
  5. Enteritis (inflammation of the small intestine)
  6. Enterococcal infection
  7. Escherichia infection (bacterial infection by escherichia coli)
  8. Essential thrombocythaemia (chronic blood cancer)
  9. Exostosis (formation of new bone on the surface of a bone)
  10. Facial neuralgia (pain of face)

60+:

n/a

What are the existing conditions these people have? *

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 27 people, 71.05%
  2. Osteoporosis (bones weak and more likely to break): 27 people, 71.05%
  3. Thrombocytopenia (decrease of platelets in blood): 11 people, 28.95%
  4. Depression: 5 people, 13.16%
  5. Birth Control: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Vicodin and Mefoxin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Vicodin and Mefoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vicodin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mefoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vicodin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mefoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate and cefoxitin sodium (the active ingredients of Vicodin and Mefoxin, respectively), and Vicodin and Mefoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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