Viread and Paxil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viread (tenofovir disoproxil fumarate) and Paxil (paroxetine hydrochloride). Common drug interactions include weight decreased among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Viread and Paxil. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Viread?

Viread has active ingredients of tenofovir disoproxil fumarate. It is often used in hepatitis b. eHealthMe is studying from 51,542 Viread users. Check the latest studies of Viread.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.



On Aug, 06, 2026

90 people who take Viread and Paxil together, and have interactions are studied.

Viread and Paxil drug interactions.

What are the common drug interactions of Viread and Paxil, by gender? *:

female:

  1. Weight decreased
  2. Bone loss
  3. Fall
  4. Osteonecrosis (death of bone)
  5. Renal failure (kidney dysfunction)
  6. Upper limb fracture
  7. Multiple fractures
  8. Femur fracture
  9. Hip fracture
  10. Nephrogenic anaemia (anaemia due to kidney disease)

male:

  1. Pain
  2. Emotional distress
  3. Renal failure acute (rapid kidney dysfunction)
  4. Renal impairment (severely reduced kidney function)
  5. Death
  6. Renal injury (kidney injury)
  7. Abdominal pain
  8. Osteopenia (a condition where bone mineral density is lower than normal)
  9. Dehydration (dryness resulting from the removal of water)
  10. Fear

What are the common drug interactions of Viread and Paxil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Chronic kidney disease
  2. Emotional distress
  3. Pain
  4. Renal failure (kidney dysfunction)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Death
  7. Decreased activity
  8. Fear
  9. Impaired work ability
  10. Quality of life decreased

30-39:

  1. Bone density decreased
  2. Osteonecrosis (death of bone)
  3. Osteopenia (a condition where bone mineral density is lower than normal)
  4. Osteoporosis (bones weak and more likely to break)
  5. Emotional distress
  6. Pain
  7. Back pain
  8. Bone loss
  9. Hypokalaemia (low potassium)
  10. Mobility decreased (ability to move is reduced)

40-49:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Chronic kidney disease
  4. Emotional distress
  5. Weight decreased
  6. Nausea (feeling of having an urge to vomit)
  7. Renal impairment (severely reduced kidney function)
  8. Diarrhoea
  9. Osteoporosis (bones weak and more likely to break)
  10. Upper limb fracture

50-59:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Cough
  4. Creatinine renal clearance increased
  5. Dyspnoea (difficult or laboured respiration)
  6. Dysstasia (difficulty in standing)
  7. Dysuria (painful or difficult urination)
  8. Gait disturbance
  9. Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
  10. Mastication disorder (disease of chewing food)

60+:

  1. Pain
  2. Bone density decreased
  3. Post-traumatic stress disorder
  4. Renal impairment (severely reduced kidney function)
  5. Weight increased
  6. Dizziness
  7. Nausea (feeling of having an urge to vomit)
  8. Pneumothorax traumatic
  9. Rib fracture
  10. Anaemia (lack of blood)

What are the existing conditions these people have? *

  1. Hiv Infection: 54 people, 60.00%
  2. High Blood Pressure: 15 people, 16.67%
  3. Diabetes: 10 people, 11.11%
  4. Pain: 8 people, 8.89%
  5. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 8 people, 8.89%
  6. Stress And Anxiety: 7 people, 7.78%
  7. Neuropathy Peripheral (surface nerve damage): 7 people, 7.78%
  8. Insomnia (sleeplessness): 7 people, 7.78%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 7.78%
  10. Hypersensitivity: 6 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Viread and Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Viread:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viread and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Paxil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on tenofovir disoproxil fumarate and paroxetine hydrochloride (the active ingredients of Viread and Paxil, respectively), and Viread and Paxil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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