Viread and Valproic acid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Viread (tenofovir disoproxil fumarate) and Valproic acid (valproic acid). Common drug interactions include anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Viread and Valproic acid. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.
What is Viread?
Viread has active ingredients of tenofovir disoproxil fumarate. It is often used in hepatitis b. eHealthMe is studying from 51,542 Viread users. Check the latest studies of Viread.
What is Valproic acid?
Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.
79 people who take Viread and Valproic acid together, and have interactions are studied.

What are the common drug interactions of Viread and Valproic Acid, by gender? *:
female:
n/a
male:
- Anxiety
- Depression suicidal (suicide depressive disorder)
- Diplopia (double vision)
- Eyelid ptosis (falling of the upper or lower eyelid)
- Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
- Mitochondrial toxicity (a condition in which the mitochondria of a body's cells become damaged or decline significantly in number;)
- Psychomotor retardation (motor mental retardation)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Emotional distress
- Osteoporosis (bones weak and more likely to break)
What are the common drug interactions of Viread and Valproic Acid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abdominal discomfort
- Abdominal pain upper
- C-reactive protein increased
- Cholecystitis acute (rapid infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Depressed level of consciousness
- Muscle spasms (muscle contraction)
- Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
- Pyrexia (fever)
40-49:
- Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
- Renal failure acute (rapid kidney dysfunction)
- Asthenia (weakness)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Cytomegalovirus infection
- Dehydration (dryness resulting from the removal of water)
- Diabetes mellitus inadequate control
- Diabetic hyperglycaemic coma (diabetic coma occurs when blood sugar gets too high and the body becomes severely dehydrated)
- Difficulty in walking
- Drug toxicity
50-59:
- Psychiatric decompensation (worsening of symptoms to the state of a serious mental disorder)
- Tearfulness (excess tearing)
- Depression
- Diplopia (double vision)
- Eyelid ptosis (falling of the upper or lower eyelid)
- Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
- Mitochondrial toxicity (a condition in which the mitochondria of a body's cells become damaged or decline significantly in number;)
- Psychomotor retardation (motor mental retardation)
- Hospitalisation
- Anxiety
60+:
- Anaemia (lack of blood)
- Depression
- Dizziness
What are the existing conditions these people have? *
- Hiv Infection: 77 people, 97.47%
- Depression: 69 people, 87.34%
- Bipolar Disorder (mood disorder): 69 people, 87.34%
- Psychotic Disorder: 67 people, 84.81%
- Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 16 people, 20.25%
* Approximation only. Some reports may have incomplete information.
Do you take Viread and Valproic acid?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Viread (51,542 reports)
- Valproic acid (36,193 reports)
Browse all drug interactions of Viread and Valproic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Viread:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Valproic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Viread and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Valproic acid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Hwabejire JO, Lu J, Liu B, Li Y, Halaweish I, Alam HB, "Valproic acid for the treatment of hemorrhagic shock: a dose-optimization study", journal of surgical research, 2014 Jan .
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Hwabejire JO, Lu J, Liu B, Li Y, Halaweish I, Alam HB, "Valproic acid for the treatment of hemorrhagic shock: a dose-optimization study", journal of surgical research, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on tenofovir disoproxil fumarate and valproic acid (the active ingredients of Viread and Valproic acid, respectively), and Viread and Valproic acid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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