Vistaril and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Vistaril (hydroxyzine hydrochloride) and Digoxin (digoxin). Common drug interactions include aortic valve incompetence among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Vistaril and Digoxin. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

On Jul, 17, 2026

66 people who take Vistaril and Digoxin together, and have interactions are studied.

What are the common drug interactions of Vistaril and Digoxin, by gender? *:

female:

Aortic valve incompetence
Mitral valve incompetence (inefficient heart valve)
Tricuspid valve incompetence (inefficient heart valve)
Hypertension (high blood pressure)
Oedema peripheral (superficial swelling)
Pericardial effusion (fluid around the heart)
Decreased appetite
Muscle spasms (muscle contraction)
Pleural effusion (water on the lungs)
Road traffic accident

male:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Respiratory failure (inadequate gas exchange by the respiratory system)
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Pneumonia
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiomegaly (increased size of heart than normal)
Chest discomfort

What are the common drug interactions of Vistaril and Digoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Hypertension (high blood pressure)
Injury
Oedema peripheral (superficial swelling)
Pericardial effusion (fluid around the heart)
Asthenia (weakness)
Hyperlipidaemia (presence of excess lipids in the blood)
Aortic valve incompetence
Palpitations (feelings or sensations that your heart is pounding or racing)
Road traffic accident

60+:

Pain
Dizziness
Atelectasis (partial or complete collapse of the lung)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Contusion (a type of hematoma of tissue in which capillaries)
Depression
Injury
Pyrexia (fever)
Renal failure (kidney dysfunction)
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the existing conditions these people have? *

Cardiac Failure Congestive: 11 people, 16.67%
High Blood Pressure: 10 people, 15.15%
High Blood Cholesterol: 10 people, 15.15%
Pain: 9 people, 13.64%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 12.12%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 12.12%
Breast Cancer Metastatic: 8 people, 12.12%
Diabetes: 7 people, 10.61%
Type 2 Diabetes: 4 people, 6.06%
Dyspnea (difficult or laboured breathing): 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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